Aliases for PDE9A Gene
External Ids for PDE9A Gene
The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for PDE9A Gene
PDE9A (Phosphodiesterase 9A) is a Protein Coding gene. Among its related pathways are Platelet homeostasis and Hemostasis. GO annotations related to this gene include 3,5-cyclic-nucleotide phosphodiesterase activity and 3,5-cyclic-GMP phosphodiesterase activity. An important paralog of this gene is PDE7A.
UniProtKB/Swiss-Prot for PDE9A Gene
Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.