Aliases for UBE2J1 Gene
- Ubiquitin-Conjugating Enzyme E2, J1 2 3
- Ubiquitin-Conjugating Enzyme E2, J1 (UBC6 Homolog, Yeast) 2 3
- Yeast Ubiquitin-Conjugating Enzyme UBC6 Homolog E 3 4
- Non-Canonical Ubiquitin-Conjugating Enzyme 1 3 4
- HSUBC6e 3 4
- NCUBE-1 3 4
- NCUBE1 3 4
- Ubiquitin-Conjugating Enzyme E2, J1, U 3
- Ubiquitin-Conjugating Enzyme E2 J1 3
External Ids for UBE2J1 Gene
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]
GeneCards Summary for UBE2J1 Gene
UBE2J1 (Ubiquitin-Conjugating Enzyme E2, J1) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Remodeling of Adherens Junctions. GO annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is UBE2J2.
UniProtKB/Swiss-Prot for UBE2J1 Gene
Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).