Aliases for CRIM1 Gene
External Ids for CRIM1 Gene
Previous HGNC Symbols for CRIM1 Gene
Previous GeneCards Identifiers for CRIM1 Gene
This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]
GeneCards Summary for CRIM1 Gene
CRIM1 (Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like)) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase inhibitor activity and enzyme inhibitor activity. An important paralog of this gene is KCP.
UniProtKB/Swiss-Prot for CRIM1 Gene
May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.