Aliases for GLRX5 Gene
External Ids for GLRX5 Gene
Previous Symbols for GLRX5 Gene
This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010]
GeneCards Summary for GLRX5 Gene
GLRX5 (Glutaredoxin 5) is a Protein Coding gene. Diseases associated with GLRX5 include pearson syndrome and spasticity-ataxia-gait anomalies syndrome. Among its related pathways are PAK Pathway. GO annotations related to this gene include electron carrier activity and 2 iron, 2 sulfur cluster binding.
UniProtKB/Swiss-Prot for GLRX5 Gene
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1