Aliases for TAS2R13 Gene
External Ids for TAS2R13 Gene
Previous GeneCards Identifiers for TAS2R13 Gene
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
GeneCards Summary for TAS2R13 Gene
TAS2R13 (Taste Receptor, Type 2, Member 13) is a Protein Coding gene. Diseases associated with TAS2R13 include colorectal cancer. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include taste receptor activity. An important paralog of this gene is TAS2R42.
UniProtKB/Swiss-Prot for TAS2R13 Gene
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5