Aliases for IGK Gene
Previous HGNC Symbols for IGK Gene
- IGK@
Previous GeneCards Identifiers for IGK Gene
- GC02P089931
- GC02P090039
Summaries for IGK Gene
GeneCards Summary for IGK Gene
IGK (Immunoglobulin Kappa Locus) is a Protein Coding gene. Among its related pathways are Development Angiotensin activation of ERK and Immune response Fc epsilon RI pathway.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGK Gene
Genomics for IGK Gene
Regulatory Element Products
Genomic Location for IGK Gene
- Chromosome:
- 2
- Start:
- 89,851,758 bp from pter
- End:
- 90,235,368 bp from pter
- Size:
- 383,611 bases
- Orientation:
- Plus strand
Genomic View for IGK Gene
Genes around IGK on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2p11.2 by Entrez Gene
- 2p11.2 by HGNC
IGK Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IGK Gene
No data available for Regulatory Elements for IGK Gene
Proteins for IGK Gene
Post-translational modifications for IGK Gene
No Post-translational modifications
Antibody Products
- Novus Biologicals Antibodies for IGK
- Search GeneTex for Antibodies for IGK
-
Santa Cruz Biotechnology (SCBT) Antibodies for IGK
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for IGK
- Origene Custom Protein Services for IGK
- Search GeneTex for Proteins for IGK
Assay Products
No data available for DME Specific Peptides for IGK Gene
Domains & Families for IGK Gene
Gene Families for IGK Gene
Suggested Antigen Peptide Sequences for IGK Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains and UniProtKB/Swiss-Prot for IGK Gene
Function for IGK Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGK
-
- Search ViGene Biosciences for IGK
CRISPR Products
- Browse CRISPR knockouts for IGK
miRNA Products
- Search ViGene Biosciences for IGK
Inhibitory RNA Products
- Search ViGene Biosciences for IGK
Clone Products
- GenScript: Custom all cDNA clones Services for IGK
- Sino Biological Human cDNA Clone for IGK
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IGK
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGK
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for IGK
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGK Gene
Localization for IGK Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGK Gene
Pathways & Interactions for IGK Gene
Pathways by source for IGK Gene
7 GeneGo (Thomson Reuters) pathways for IGK Gene
Interacting Proteins for IGK Gene
No data available for SIGNOR curated interactions for IGK Gene
Transcripts for IGK Gene
mRNA/cDNA for IGK Gene
- (859) Additional mRNA sequences :
Unigene Clusters for IGK Gene
CRISPR Products
- Browse CRISPR knockouts for IGK
miRNA Products
- Search ViGene Biosciences for IGK
Inhibitory RNA Products
- Search ViGene Biosciences for IGK
Clone Products
- GenScript: Custom all cDNA clones Services for IGK
- Sino Biological Human cDNA Clone for IGK
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IGK
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGK
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for IGK Gene
NURSA nuclear receptor signaling pathways regulating expression of IGK Gene:
IGKSOURCE GeneReport for Unigene cluster for IGK Gene:
Hs.719895Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGK Gene
Orthologs for IGK Gene
No data available for Orthologs and Evolution for IGK Gene
Paralogs for IGK Gene
No data available for Paralogs for IGK Gene
Variants for IGK Gene
Relevant External Links for IGK Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- IGK
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGK Gene
Disorders for IGK Gene
Relevant External Links for IGK
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- IGK
No disorders were found for IGK Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGK Gene
Publications for IGK Gene
- Analysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia. (PMID: 16622520) Belessi C. … Laoutaris N. (Mol. Med. 2005) 3 22 64
- Immunoglobulin kappa variable region gene selection during early human B cell development in health and systemic lupus erythematosus. (PMID: 25700344) Hehle V. … Spencer J. (Mol. Immunol. 2015) 3 64
- IGK with conserved IGI9V/IGI9J repertoire is expressed in acute myeloid leukemia and promotes leukemic cell migration. (PMID: 26429876) Wang C. … Yin C.C. (Oncotarget 2015) 3 64
- Role of kappa-lamda light-chain constant-domain switch in the structure and functionality of A17 reactibody. (PMID: 24598740) Ponomarenko N. … Gabibov A. (Acta Crystallogr. D 2014) 3 64
- Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts. (PMID: 25149546) Hutchinson A.T. … Raison R.L. (Hum. Immunol. 2014) 3 64
Products for IGK Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for IGK
- Origene Custom Protein Services for IGK
- Browse OriGene Inhibitory RNA Products For IGK
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for IGK
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For IGK
- GenScript: Custom all cDNA clones Services for IGK
- GenScript Custom Purified and Recombinant Proteins Services for IGK
- GenScript Custom Assay Services for IGK
- GenScript Custom overexpressing Cell Line Services for IGK
- Browse GenScript CRISPR for IGK
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IGK
- Sino Biological Human cDNA Clone for IGK
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for IGK
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Search ViGene Biosciences for IGK
- Santa Cruz Biotechnology (SCBT) Antibodies for IGK
- Search Santa Cruz Biotechnology (SCBT) for IGK siRNA/shRNA
- Browse Santa Cruz Biotechnology (SCBT) for IGK CRISPR
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGK
- VectorBuilder custom plasmid, inducible vectors for IGK
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGK
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for IGK Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer