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IGK Gene(Protein Coding)

Immunoglobulin Kappa Locus

GCID:
GC02P089854
GIFtS:
19
Genes Participants
UDN Logo

Aliases for IGK Gene

Aliases for IGK Gene

  • Immunoglobulin Kappa Locus 2 3
  • IGK@ 3

External Ids for IGK Gene

Previous HGNC Symbols for IGK Gene

  • IGK@

Previous GeneCards Identifiers for IGK Gene

  • GC02P089931
  • GC02P090039

Summaries for IGK Gene

GeneCards Summary for IGK Gene

IGK (Immunoglobulin Kappa Locus) is a Protein Coding gene. Among its related pathways are Development Angiotensin activation of ERK and Immune response Fc epsilon RI pathway.

Gene Wiki entry for IGK Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGK Gene

Genomics for IGK Gene

Products:

  1. Regulatory Element

Genomic Location for IGK Gene

Chromosome:
2
Start:
89,851,758 bp from pter
End:
90,235,368 bp from pter
Size:
383,611 bases
Orientation:
Plus strand

Genomic View for IGK Gene

Genes around IGK on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGK Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for IGK Gene

No data available for Regulatory Elements for IGK Gene

Proteins for IGK Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for IGK Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGK Gene

Domains & Families for IGK Gene

Gene Families for IGK Gene

HGNC:

Suggested Antigen Peptide Sequences for IGK Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGK: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for IGK Gene

Function for IGK Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGK Gene

Localization for IGK Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGK Gene

Pathways & Interactions for IGK Gene

genes like me logo Genes that share pathways with IGK: view

Interacting Proteins for IGK Gene

Gene Ontology (GO) - Biological Process for IGK Gene

None

No data available for SIGNOR curated interactions for IGK Gene

Drugs & Compounds for IGK Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for IGK Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for IGK Gene

(859) Additional mRNA sequences :

Unigene Clusters for IGK Gene

Immunoglobulin kappa locus:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGK Gene

No ASD Table

Relevant External Links for IGK Gene

GeneLoc Exon Structure for
IGK
ECgene alternative splicing isoforms for
IGK

Expression for IGK Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGK Gene

mRNA expression in normal human tissues for IGK Gene
mRNA expression by BioGPS for IGK Gene

NURSA nuclear receptor signaling pathways regulating expression of IGK Gene:

IGK

SOURCE GeneReport for Unigene cluster for IGK Gene:

Hs.719895
genes like me logo Genes that share expression patterns with IGK: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGK Gene

Orthologs for IGK Gene

No data available for Orthologs and Evolution for IGK Gene

Paralogs for IGK Gene

No data available for Paralogs for IGK Gene

Variants for IGK Gene

Relevant External Links for IGK Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IGK

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGK Gene

Disorders for IGK Gene

Relevant External Links for IGK

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IGK

No disorders were found for IGK Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGK Gene

Publications for IGK Gene

  1. Analysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia. (PMID: 16622520) Belessi C. … Laoutaris N. (Mol. Med. 2005) 3 22 64
  2. IGK with conserved IGI9V/IGI9J repertoire is expressed in acute myeloid leukemia and promotes leukemic cell migration. (PMID: 26429876) Wang C. … Yin C.C. (Oncotarget 2015) 3 64
  3. Immunoglobulin kappa variable region gene selection during early human B cell development in health and systemic lupus erythematosus. (PMID: 25700344) Hehle V. … Spencer J. (Mol. Immunol. 2015) 3 64
  4. Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts. (PMID: 25149546) Hutchinson A.T. … Raison R.L. (Hum. Immunol. 2014) 3 64
  5. Role of kappa-lamda light-chain constant-domain switch in the structure and functionality of A17 reactibody. (PMID: 24598740) Ponomarenko N. … Gabibov A. (Acta Crystallogr. D 2014) 3 64

Products for IGK Gene

Sources for IGK Gene

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