Aliases for IGK Gene
Previous HGNC Symbols for IGK Gene
- IGK@
Previous GeneCards Identifiers for IGK Gene
- GC02P089931
- GC02P090039
Summaries for IGK Gene
GeneCards Summary for IGK Gene
IGK (Immunoglobulin Kappa Locus) is a Protein Coding gene. Among its related pathways are Immune response Fc epsilon RI pathway and Immune response Lectin induced complement pathway.
Additional gene information for IGK Gene
- Monarch Initiative
- Search for IGK at DataMed
- Search for IGK at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGK Gene
Genomics for IGK Gene
GeneHancer (GH) Regulatory Elements for IGK Gene
Promoters and enhancers for IGK Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH02I089909 | Enhancer | 0.5 | Ensembl | 0.2 | +57.8 | 57789 | 0.5 | CTCF SRF ZNF654 SMC3 ELF1 RAD21 | IGKV1D-33 IGKV3D-34 IGK | |
| GH02I090100 | Promoter | 0.5 | EPDnew | 0.1 | +248.5 | 248464 | 0.1 | GC02M090100 IGKV1D-16 IGK |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around IGK on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for IGK Gene
Genomic Locations for IGK Gene
- chr2:89,851,758-90,235,368
- (GRCh38/hg38)
- Size:
- 383,611 bases
- Orientation:
- Plus strand
- chr2:89,890,568-90,274,235
- (GRCh37/hg19)
Genomic View for IGK Gene
Genes around IGK on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2p11.2 by Entrez Gene
- 2p11.2 by HGNC
IGK Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IGK Gene
Proteins for IGK Gene
Post-translational modifications for IGK Gene
No Post-translational modifications
Antibody Products
- Novus Biologicals Antibodies for IGK
- antibodies-online: Search results for available IGK related products ranked by validation data
- Search GeneTex for Antibodies for IGK
-
Santa Cruz Biotechnology (SCBT) Antibodies for IGK
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for IGK
- Origene Custom Protein Services for IGK
- antibodies-online: Search results for available IGK related products ranked by validation data
- Search GeneTex for Proteins for IGK
Assay Products
- antibodies-online: Search results for available IGK related products ranked by validation data
No data available for DME Specific Peptides for IGK Gene
Domains & Families for IGK Gene
Gene Families for IGK Gene
Suggested Antigen Peptide Sequences for IGK Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains and UniProtKB/Swiss-Prot for IGK Gene
Function for IGK Gene
Phenotypes From GWAS Catalog for IGK Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGK
-
- Search ViGene Biosciences for IGK
CRISPR Products
- Browse CRISPR knockouts for IGK
- genomics-online: gRNA clones - Search results for available IGK gene related products
miRNA Products
- Search ViGene Biosciences for IGK
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available IGK gene related products
- Search ViGene Biosciences for IGK
Clone Products
- GenScript: Custom all cDNA clones Services for IGK
- Sino Biological Human cDNA Clone for IGK
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IGK
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGK
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available IGK gene related products
- orf clones - Search results for available IGK gene related products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGK Gene
Localization for IGK Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for IGK Gene
Pathways & Interactions for IGK Gene
Pathways by source for IGK Gene
7 GeneGo (Thomson Reuters) pathways for IGK Gene
Interacting Proteins for IGK Gene
No data available for SIGNOR curated interactions for IGK Gene
Transcripts for IGK Gene
mRNA/cDNA for IGK Gene
- (859) Additional mRNA sequences :
Unigene Clusters for IGK Gene
CRISPR Products
- Browse CRISPR knockouts for IGK
- genomics-online: gRNA clones - Search results for available IGK gene related products
miRNA Products
- Search ViGene Biosciences for IGK
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available IGK gene related products
- Search ViGene Biosciences for IGK
Clone Products
- GenScript: Custom all cDNA clones Services for IGK
- Sino Biological Human cDNA Clone for IGK
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IGK
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGK
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available IGK gene related products
- orf clones - Search results for available IGK gene related products
Expression for IGK Gene
NURSA nuclear receptor signaling pathways regulating expression of IGK Gene:
IGKSOURCE GeneReport for Unigene cluster for IGK Gene:
Hs.719895Primer Products
- genomics-online: primer clones - Search results for available IGK gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGK Gene
Orthologs for IGK Gene
No data available for Orthologs and Evolution for IGK Gene
Paralogs for IGK Gene
No data available for Paralogs for IGK Gene
Variants for IGK Gene
Additional Variant Information for IGK Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- IGK
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGK Gene
Disorders for IGK Gene
Additional Disease Information for IGK
No disorders were found for IGK Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGK Gene
Publications for IGK Gene
- Analysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia. (PMID: 16622520) Belessi C … Laoutaris N (Molecular medicine (Cambridge, Mass.) 2005) 3 22 58
- IGK with conserved IGΚV/IGΚJ repertoire is expressed in acute myeloid leukemia and promotes leukemic cell migration. (PMID: 26429876) Wang C … Yin CC (Oncotarget 2015) 3 58
- Immunoglobulin kappa variable region gene selection during early human B cell development in health and systemic lupus erythematosus. (PMID: 25700344) Hehle V … Spencer J (Molecular immunology 2015) 3 58
- Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts. (PMID: 25149546) Hutchinson AT … Raison RL (Human immunology 2014) 3 58
- Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody. (PMID: 24598740) Ponomarenko N … Gabibov A (Acta crystallographica. Section D, Biological crystallography 2014) 3 58
Products for IGK Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for IGK
- Origene Custom Protein Services for IGK
- Browse OriGene Inhibitory RNA Products For IGK
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for IGK
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For IGK
- GenScript: Custom all cDNA clones Services for IGK
- GenScript Custom Purified and Recombinant Proteins Services for IGK
- GenScript Custom Assay Services for IGK
- GenScript Custom overexpressing Cell Line Services for IGK
- Browse GenScript CRISPR for IGK
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IGK
- Sino Biological Human cDNA Clone for IGK
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for IGK
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGK
- VectorBuilder custom plasmid, inducible vectors for IGK
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGK
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available IGK related products ranked by validation data
- antibodies-online: Search results for available IGK related products ranked by validation data
- antibodies-online: Search results for available IGK related products ranked by validation data
- Search GeneTex for Antibodies for IGK
- Search GeneTex for Proteins for IGK
- Search ViGene Biosciences for IGK
- Santa Cruz Biotechnology (SCBT) Antibodies for IGK
- Search Santa Cruz Biotechnology (SCBT) for IGK siRNA/shRNA
- Browse Santa Cruz Biotechnology (SCBT) for IGK CRISPR
- genomics-online: cdna clones - Search results for available IGK gene related products
- orf clones - Search results for available IGK gene related products
- genomics-online: gRNA clones - Search results for available IGK gene related products
- genomics-online: primer clones - Search results for available IGK gene related products
- genomics-online: shRNA clones - Search results for available IGK gene related products
Sources for IGK Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew