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Aliases for OR3A1 Gene

Aliases for OR3A1 Gene

  • Olfactory Receptor, Family 3, Subfamily A, Member 1 2 3
  • Olfactory Receptor OR17-15 3 4
  • Olfactory Receptor 17-40 3 4
  • OLFRA03 3 4
  • OR17-40 3 4
  • Olfactory Receptor 3A1 3
  • OR17-82 3
  • OR40 3

External Ids for OR3A1 Gene

Previous GeneCards Identifiers for OR3A1 Gene

  • GC17M003509
  • GC17M003536
  • GC17M003145
  • GC17M003401
  • GC17M003141
  • GC17M003194

Summaries for OR3A1 Gene

Entrez Gene Summary for OR3A1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR3A1 Gene

OR3A1 (Olfactory Receptor, Family 3, Subfamily A, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR3A2.

UniProtKB/Swiss-Prot for OR3A1 Gene

  • Odorant receptor.

Gene Wiki entry for OR3A1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR3A1 Gene

Genomics for OR3A1 Gene

Regulatory Elements for OR3A1 Gene

Genomic Location for OR3A1 Gene

3,291,635 bp from pter
3,292,600 bp from pter
966 bases
Minus strand

Genomic View for OR3A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR3A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR3A1 Gene

Proteins for OR3A1 Gene

  • Protein details for OR3A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 3A1
    Protein Accession:
    Secondary Accessions:
    • Q4VB06
    • Q6IFM4

    Protein attributes for OR3A1 Gene

    315 amino acids
    Molecular mass:
    34609 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR3A1 Gene

Proteomics data for OR3A1 Gene at MOPED

Post-translational modifications for OR3A1 Gene

  • Glycosylation at Asn8
  • Modification sites at PhosphoSitePlus

Other Protein References for OR3A1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR3A1 Gene

Domains for OR3A1 Gene

Gene Families for OR3A1 Gene

Protein Domains for OR3A1 Gene

Suggested Antigen Peptide Sequences for OR3A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR3A1: view

Function for OR3A1 Gene

Molecular function for OR3A1 Gene

GENATLAS Biochemistry:
olfactory receptor gene family 3,subfamily A,member 1,G protein coupled receptor superfamily,with odorant ligand
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR3A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR3A1: view

Phenotypes for OR3A1 Gene

GenomeRNAi human phenotypes for OR3A1:
genes like me logo Genes that share phenotypes with OR3A1: view

Animal Model Products

CRISPR Products

miRNA for OR3A1 Gene

miRTarBase miRNAs that target OR3A1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR3A1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for OR3A1 Gene

Localization for OR3A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR3A1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR3A1 Gene COMPARTMENTS Subcellular localization image for OR3A1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR3A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR3A1: view

Pathways for OR3A1 Gene

genes like me logo Genes that share pathways with OR3A1: view

Pathways by source for OR3A1 Gene

1 KEGG pathway for OR3A1 Gene

Gene Ontology (GO) - Biological Process for OR3A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction NAS 8921386
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR3A1: view

Transcripts for OR3A1 Gene

mRNA/cDNA for OR3A1 Gene

(2) Selected AceView cDNA sequences:
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR3A1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR3A1 Gene

No ASD Table

Relevant External Links for OR3A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR3A1 Gene

mRNA expression in normal human tissues for OR3A1 Gene

mRNA differential expression in normal tissues according to GTEx for OR3A1 Gene

This gene is overexpressed in Testis (14.3).

SOURCE GeneReport for Unigene cluster for OR3A1 Gene Hs.647410

genes like me logo Genes that share expressions with OR3A1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR3A1 Gene

Orthologs for OR3A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR3A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR3A1 35
  • 89.07 (n)
  • 86.94 (a)
OR3A1 36
  • 84 (a)
(Canis familiaris)
Mammalia LOC491212 35
  • 87.62 (n)
  • 86.35 (a)
OR3A1 36
  • 84 (a)
(Mus musculus)
Mammalia Olfr402 35
  • 83.28 (n)
  • 82.86 (a)
Olfr402 16
Olfr401 36
  • 81 (a)
Olfr402 36
  • 83 (a)
Olfr410 36
  • 85 (a)
(Pan troglodytes)
Mammalia LOC468152 35
  • 98.52 (n)
  • 97.78 (a)
OR3A1 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Olr1517 35
  • 84.87 (n)
  • 84.76 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 46 (a)
(Gallus gallus)
Aves -- 36
  • 37 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 39 (a)
Species with no ortholog for OR3A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR3A1 Gene

Gene Tree for OR3A1 (if available)
Gene Tree for OR3A1 (if available)

Paralogs for OR3A1 Gene

Paralogs for OR3A1 Gene

(456) SIMAP similar genes for OR3A1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR3A1: view

Variants for OR3A1 Gene

Sequence variations from dbSNP and Humsavar for OR3A1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs703903 - 3,292,209(+) GGAAT(A/C/T)GGTCA missense, reference
rs2625458 -- 3,293,228(+) AATGG(A/G)TATAT upstream-variant-2KB
rs2625459 -- 3,293,612(+) TAAAC(A/C)AGAAA upstream-variant-2KB
rs2676604 -- 3,292,678(+) TTGCC(C/T)GGCCC upstream-variant-2KB
rs2855672 -- 3,294,072(-) TTTGT(C/T)ACATA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR3A1 Gene

Variant ID Type Subtype PubMed ID
esv2660206 CNV Deletion 23128226
nsv907553 CNV Loss 21882294
nsv907555 CNV Loss 21882294
nsv907557 CNV Loss 21882294
dgv3041n71 CNV Gain 21882294
nsv457638 CNV Gain 19166990
nsv470570 CNV Gain 18288195
nsv457639 CNV Gain 19166990
nsv827859 CNV Gain 20364138
nsv907560 CNV Gain 21882294
nsv907561 CNV Gain 21882294
nsv907562 CNV Gain 21882294

Relevant External Links for OR3A1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR3A1 Gene

Disorders for OR3A1 Gene

No disorders were found for OR3A1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR3A1 Gene

Publications for OR3A1 Gene

  1. Olfactory receptor-encoding genes and pseudogenes are expressed in humans. (PMID: 8647456) Crowe M.L. … Connerton I.F. (Gene 1996) 2 3 4
  2. Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity. (PMID: 8921386) Glusman G. … Lancet D. (Genomics 1996) 2 3 4
  3. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G. … Lancet D. (Genomics 2000) 3 4
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for OR3A1 Gene

Sources for OR3A1 Gene

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