Aliases for NPPC Gene
External Ids for NPPC Gene
Previous GeneCards Identifiers for NPPC Gene
The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. [provided by RefSeq, Sep 2011]
GeneCards Summary for NPPC Gene
NPPC (Natriuretic Peptide C) is a Protein Coding gene. Diseases associated with NPPC include intracranial hypertension and acromesomelic dysplasia. Among its related pathways are Neuroscience and Glial Cell Differentiation. GO annotations related to this gene include protein homodimerization activity and hormone activity.
UniProtKB/Swiss-Prot for NPPC Gene
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity).