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Aliases for NFKB1 Gene

Aliases for NFKB1 Gene

  • Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1 2 3 4
  • DNA-Binding Factor KBF1 3 4
  • EBP-1 3 4
  • Nuclear Factor Kappa-B DNA Binding Subunit 3
  • Nuclear Factor NF-Kappa-B P50 Subunit 3
  • DNA Binding Factor KBF1 3
  • NF-Kappabeta 3
  • NF-Kappa-B 3
  • NF-KappaB 3
  • NFKB-P105 3
  • NFKB-P50 3
  • NFkappaB 3
  • NF-KB1 3
  • P105 3
  • KBF1 3
  • P50 3

External Ids for NFKB1 Gene

Previous GeneCards Identifiers for NFKB1 Gene

  • GC04P103821
  • GC04P103880
  • GC04P103779
  • GC04P103641
  • GC04P103422
  • GC04P099158

Summaries for NFKB1 Gene

Entrez Gene Summary for NFKB1 Gene

  • This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

GeneCards Summary for NFKB1 Gene

NFKB1 (Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1) is a Protein Coding gene. Diseases associated with NFKB1 include immunodeficiency, common variable, 12 and barrett esophagus/esophageal adenocarcinoma. Among its related pathways are PI3K-Akt signaling pathway and MAPK signaling pathway. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is RELB.

UniProtKB/Swiss-Prot for NFKB1 Gene

  • NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function, although processing of NFKB1/p105 also appears to occur post-translationally. p50 binds to the kappa-B consensus sequence 5-GGRNNYYCC-3, located in the enhancer region of genes involved in immune response and acute phase reactions. In a complex with MAP3K8, NFKB1/p105 represses MAP3K8-induced MAPK signaling; active MAP3K8 is released by proteasome-dependent degradation of NFKB1/p105.

Tocris Summary for NFKB1 Gene

  • NF-kappaB (nuclear factor-kappa B) is a rapidly acting primary transcription factor found in all cell types. It is involved in the cellular responses to stimuli such as cytokines and stress and plays a key role in regulating the immunological response to infections.

Gene Wiki entry for NFKB1 Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NFKB1 Gene

Genomics for NFKB1 Gene

Regulatory Elements for NFKB1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NFKB1 Gene

Chromosome:
4
Start:
102,501,329 bp from pter
End:
102,617,302 bp from pter
Size:
115,974 bases
Orientation:
Plus strand

Genomic View for NFKB1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NFKB1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NFKB1 Gene

Proteins for NFKB1 Gene

  • Protein details for NFKB1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P19838-NFKB1_HUMAN
    Recommended name:
    Nuclear factor NF-kappa-B p105 subunit
    Protein Accession:
    P19838
    Secondary Accessions:
    • A8K5Y5
    • B3KVE8
    • Q68D84
    • Q86V43
    • Q8N4X7
    • Q9NZC0

    Protein attributes for NFKB1 Gene

    Size:
    968 amino acids
    Molecular mass:
    105356 Da
    Quaternary structure:
    • Component of the NF-kappa-B p65-p50 complex. Component of the NF-kappa-B p65-p50 complex. Homodimer; component of the NF-kappa-B p50-p50 complex. Component of the NF-kappa-B p105-p50 complex. Component of the NF-kappa-B p50-c-Rel complex. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation and DNA-binding. Interacts with SPAG9 and UNC5CL. NFKB1/p105 interacts with CFLAR; the interaction inhibits p105 processing into p50. NFKB1/p105 forms a ternary complex with MAP3K8 and TNIP2. Interacts with GSK3B; the interaction prevents processing of p105 to p50. NFKB1/p50 interacts with NFKBIE. NFKB1/p50 interacts with NFKBIZ. Nuclear factor NF-kappa-B p50 subunit interacts with NFKBID (By similarity). Directly interacts with MEN1. Interacts with HIF1AN.

    Three dimensional structures from OCA and Proteopedia for NFKB1 Gene

    Alternative splice isoforms for NFKB1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NFKB1 Gene

Proteomics data for NFKB1 Gene at MOPED

Post-translational modifications for NFKB1 Gene

  • Phosphorylation at Ser-903 and Ser-907 primes p105 for proteolytic processing in response to TNF-alpha stimulation. Phosphorylation at Ser-927 and Ser-932 are required for BTRC/BTRCP-mediated proteolysis.
  • Polyubiquitination seems to allow p105 processing.
  • S-nitrosylation of Cys-61 affects DNA binding.
  • The covalent modification of cysteine by 15-deoxy-Delta12,14-prostaglandin-J2 is autocatalytic and reversible. It may occur as an alternative to other cysteine modifications, such as S-nitrosylation and S-palmitoylation
  • While translation occurs, the particular unfolded structure after the GRR repeat promotes the generation of p50 making it an acceptable substrate for the proteasome. This process is known as cotranslational processing. The processed form is active and the unprocessed form acts as an inhibitor (I kappa B-like), being able to form cytosolic complexes with NF-kappa B, trapping it in the cytoplasm. Complete folding of the region downstream of the GRR repeat precludes processing.
  • Ubiquitination at Lys 856
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for NFKB1 Gene

Domains & Families for NFKB1 Gene

Gene Families for NFKB1 Gene

Suggested Antigen Peptide Sequences for NFKB1 Gene

Graphical View of Domain Structure for InterPro Entry

P19838

UniProtKB/Swiss-Prot:

NFKB1_HUMAN :
  • The C-terminus of p105 might be involved in cytoplasmic retention, inhibition of DNA-binding, and transcription activation
  • Contains 7 ANK repeats.
Domain:
  • The C-terminus of p105 might be involved in cytoplasmic retention, inhibition of DNA-binding, and transcription activation
  • Glycine-rich region (GRR) appears to be a critical element in the generation of p50
  • Contains 1 death domain.
  • Contains 1 RHD (Rel-like) domain.
Similarity:
  • Contains 7 ANK repeats.
genes like me logo Genes that share domains with NFKB1: view

Function for NFKB1 Gene

Molecular function for NFKB1 Gene

GENATLAS Biochemistry:
nuclear transcription factor of kappa light chain gene enhancer in B cells,1,(encoding the p105 precursor and the amino-terminal active p50 subunit),NF-kappa B/REL family
UniProtKB/Swiss-Prot Function:
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function, although processing of NFKB1/p105 also appears to occur post-translationally. p50 binds to the kappa-B consensus sequence 5-GGRNNYYCC-3, located in the enhancer region of genes involved in immune response and acute phase reactions. In a complex with MAP3K8, NFKB1/p105 represses MAP3K8-induced MAPK signaling; active MAP3K8 is released by proteasome-dependent degradation of NFKB1/p105.
UniProtKB/Swiss-Prot Induction:
By phorbol ester and TNF

Gene Ontology (GO) - Molecular Function for NFKB1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000975 regulatory region DNA binding IDA 17426251
GO:0000976 transcription regulatory region sequence-specific DNA binding IDA 18718911
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA 7959007
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IDA 1406630
GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding IDA 1406630
genes like me logo Genes that share ontologies with NFKB1: view
genes like me logo Genes that share phenotypes with NFKB1: view

Animal Models for NFKB1 Gene

MGI Knock Outs for NFKB1:

Transcription Factor Targets for NFKB1 Gene

Selected GeneGlobe predicted Target genes for NFKB1
Targeted motifs for NFKB1 Gene
HOMER Transcription Factor Regulatory Elements motif NFKB1
  • Consensus sequence: GGGGGAATCCCC Submotif: canonical Cell Type: Monocyte

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NFKB1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) for NFKB1 Gene

Localization for NFKB1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NFKB1 Gene

Nucleus. Cytoplasm. Note=Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NFKB1 Gene COMPARTMENTS Subcellular localization image for NFKB1 gene
Compartment Confidence
nucleus 5
mitochondrion 4
cytosol 3
extracellular 1

Gene Ontology (GO) - Cellular Components for NFKB1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 11819787
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm IDA 11819787
GO:0005739 mitochondrion IDA --
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with NFKB1: view

Pathways & Interactions for NFKB1 Gene

SuperPathways for NFKB1 Gene

Superpath Contained pathways
1 MyD88 cascade initiated on plasma membrane
2 TWEAK Pathway
3 4-1BB Pathway
4 Cytosolic sensors of pathogen-associated DNA
5 Toll-Like receptor Signaling Pathways
genes like me logo Genes that share pathways with NFKB1: view

Pathways by source for NFKB1 Gene

PCR Array Products

SIGNOR curated interactions for NFKB1 Gene

Activates:
Inactivates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for NFKB1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP 19881551
GO:0001818 negative regulation of cytokine production --
GO:0002223 stimulatory C-type lectin receptor signaling pathway TAS --
GO:0002224 toll-like receptor signaling pathway TAS --
GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with NFKB1: view

Drugs & Compounds for NFKB1 Gene

(42) Drugs for NFKB1 Gene - From: NovoSeek, DGIdb, ApexBio, DrugBank, Tocris, and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Thalidomide Approved, Investigational, Withdrawn Pharma inhibitor, Target, antagonist Immunomodulatory agent,sedative drug,angiogenesis inhibitor, Immunomodulatory agents, TNF-alpha synthesis inhibitor 776
Pranlukast Approved Pharma Antagonist, Target, other/unknown 3
Aspirin Approved Pharma Channel blocker, Target, antagonist 971
Triflusal Approved Pharma Target, antagonist 5
Sulfasalazine Approved Pharma Inhibition, Inhibitor NF-κB activation inhibitor 53

(2) Additional Compounds for NFKB1 Gene - From: Tocris and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
cis,trans-5'-Hydroxythalidomide
IKK 16
1186195-62-9
genes like me logo Genes that share compounds with NFKB1: view

Transcripts for NFKB1 Gene

Unigene Clusters for NFKB1 Gene

Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NFKB1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NFKB1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^
SP1: - - -
SP2: - - -
SP3: -
SP4:
SP5:

ExUns: 22 ^ 23 ^ 24a · 24b · 24c
SP1:
SP2:
SP3:
SP4:
SP5:

Relevant External Links for NFKB1 Gene

GeneLoc Exon Structure for
NFKB1
ECgene alternative splicing isoforms for
NFKB1

Expression for NFKB1 Gene

mRNA expression in normal human tissues for NFKB1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for NFKB1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (12.0) and Lymph node (10.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for NFKB1 Gene



SOURCE GeneReport for Unigene cluster for NFKB1 Gene Hs.618430

genes like me logo Genes that share expression patterns with NFKB1: view

Protein tissue co-expression partners for NFKB1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NFKB1 Gene

Orthologs for NFKB1 Gene

This gene was present in the common ancestor of animals.

Orthologs for NFKB1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia NFKB1 35
  • 88.96 (n)
  • 92 (a)
NFKB1 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NFKB1 35
  • 89.87 (n)
  • 91.49 (a)
NFKB1 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nfkb1 35
  • 84.46 (n)
  • 87.75 (a)
Nfkb1 16
Nfkb1 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia NFKB1 35
  • 99.69 (n)
  • 100 (a)
NFKB1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nfkb1 35
  • 84.38 (n)
  • 88.13 (a)
oppossum
(Monodelphis domestica)
Mammalia NFKB1 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 93 (a)
OneToMany
-- 36
  • 67 (a)
OneToMany
chicken
(Gallus gallus)
Aves NFKB1 35
  • 71.87 (n)
  • 73.79 (a)
NFKB1 36
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia nfkb1 35
  • 66.74 (n)
  • 68.97 (a)
Str.11435 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10943 35
fruit fly
(Drosophila melanogaster)
Insecta dl 37
  • 41 (a)
Rel 37
  • 34 (a)
Rel 36
  • 23 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1675 36
  • 32 (a)
OneToMany
Species with no ortholog for NFKB1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NFKB1 Gene

ENSEMBL:
Gene Tree for NFKB1 (if available)
TreeFam:
Gene Tree for NFKB1 (if available)

Paralogs for NFKB1 Gene

Paralogs for NFKB1 Gene

(3) SIMAP similar genes for NFKB1 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with NFKB1: view

Variants for NFKB1 Gene

Sequence variations from dbSNP and Humsavar for NFKB1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
VAR_016268 -
VAR_016269 -
VAR_016270 -
VAR_016271 -
VAR_016272 -

Structural Variations from Database of Genomic Variants (DGV) for NFKB1 Gene

Variant ID Type Subtype PubMed ID
nsv830020 CNV Loss 17160897
nsv4442 CNV Insertion 18451855
esv27559 CNV Loss 19812545
esv2728077 CNV Deletion 23290073

Variation tolerance for NFKB1 Gene

Residual Variation Intolerance Score: 18.99% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.96; 36.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NFKB1 Gene

HapMap Linkage Disequilibrium report
NFKB1
Human Gene Mutation Database (HGMD)
NFKB1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NFKB1 Gene

Disorders for NFKB1 Gene

MalaCards: The human disease database

(11) MalaCards diseases for NFKB1 Gene - From: OMIM, ClinVar, Orphanet, DISEASES, NovoSeek, and GeneCards

Disorder Aliases PubMed IDs
immunodeficiency, common variable, 12
  • nfkb1 deficiency
barrett esophagus/esophageal adenocarcinoma
  • barrett's esophagus
t-cell prolymphocytic leukemia
  • t-pll
common variable immunodeficiency
  • acquired agammaglobulinemia
intestinal perforation
  • perforation of intestine
- elite association
Search NFKB1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for NFKB1

Genetic Association Database (GAD)
NFKB1
Human Genome Epidemiology (HuGE) Navigator
NFKB1
Tumor Gene Database (TGDB):
NFKB1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NFKB1
genes like me logo Genes that share disorders with NFKB1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NFKB1 Gene

Publications for NFKB1 Gene

  1. A functional promoter polymorphism in NFKB1 increases susceptibility to endometriosis. (PMID: 20218898) Zhou B. … Zhang L. (DNA Cell Biol. 2010) 23 67
  2. Effects of gamma-secretase inhibitors on the growth of leukemia cells. (PMID: 20332460) Okuhashi Y. … Tohda S. (Anticancer Res. 2010) 23 67
  3. Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P. … Inskip P.D. (Cancer Epidemiol. Biomarkers Prev. 2010) 23 67
  4. Insertion/deletion polymorphism in the promoter region of NFKB1 gene increases susceptibility for superficial bladder cancer in Chinese. (PMID: 19778281) Tang T. … Li J. (DNA Cell Biol. 2010) 23 67
  5. A functional insertion/deletion polymorphism in the promoter region of NFKB1 gene increases susceptibility for nasopharyngeal carcinoma. (PMID: 19006646) Zhou B. … Zhang L. (Cancer Lett. 2009) 23 67

Products for NFKB1 Gene

  • Addgene plasmids for NFKB1

Sources for NFKB1 Gene

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