Aliases for NFIB Gene
External Ids for NFIB Gene
Previous GeneCards Identifiers for NFIB Gene
GeneCards Summary for NFIB Gene
NFIB (Nuclear Factor I B) is a Protein Coding gene. Diseases associated with NFIB include polymorphous low-grade adenocarcinoma and large intestine lipoma. Among its related pathways are Gene Expression and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. An important paralog of this gene is NFIX.
UniProtKB/Swiss-Prot for NFIB Gene
Recognizes and binds the palindromic sequence 5-TTGGCNNNNNGCCAA-3 present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.