Aliases for NFE2L1 Gene
Aliases for NFE2L1 Gene
External Ids for NFE2L1 Gene
- HGNC: 7781
- Entrez Gene: 4779
- Ensembl: ENSG00000082641
- OMIM: 163260
- UniProtKB: Q14494
Previous HGNC Symbols for NFE2L1 Gene
- TCF11
Previous GeneCards Identifiers for NFE2L1 Gene
- GC17P045831
- GC17P048606
- GC17P046467
- GC17P046600
- GC17P043480
- GC17P046125
- GC17P041494
Summaries for NFE2L1 Gene
-
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008]
GeneCards Summary for NFE2L1 Gene
NFE2L1 (Nuclear Factor, Erythroid 2 Like 1) is a Protein Coding gene. Among its related pathways are PAK Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription cofactor activity. An important paralog of this gene is NFE2L3.
UniProtKB/Swiss-Prot for NFE2L1 Gene
-
Activates erythroid-specific, globin gene expression.
Additional gene information for NFE2L1 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NFE2L1 Gene
Genomics for NFE2L1 Gene
GeneHancer (GH) Regulatory Elements for NFE2L1 Gene
Regulatory Element Products
Genomic Locations for NFE2L1 Gene
- chr17:48,048,324-48,061,545
- (GRCh38/hg38)
- Size:
- 13,222 bases
- Orientation:
- Plus strand
- chr17:46,125,686-46,138,907
- (GRCh37/hg19)
Genomic View for NFE2L1 Gene
- Cytogenetic band:
-
- 17q21.32 by Ensembl
- 17q21.32 by Entrez Gene
- 17q21.3 by HGNC


RefSeq DNA sequence for NFE2L1 Gene
Proteins for NFE2L1 Gene
-
Protein details for NFE2L1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14494-NF2L1_HUMAN
- Recommended name:
- Nuclear factor erythroid 2-related factor 1
- Protein Accession:
- Q14494
- D3DTU3
- D3DTU5
- Q12877
- Q96FN6
Protein attributes for NFE2L1 Gene
- Size:
- 772 amino acids
- Molecular mass:
- 84704 Da
- Quaternary structure:
-
- Interacts with KEAP1.
Protein Expression for NFE2L1 Gene
Post-translational modifications for NFE2L1 Gene
- Ubiquitination at isoforms=270
Other Protein References for NFE2L1 Gene
- ENSEMBL proteins:
-
- ENSP00000350072
- ENSP00000355190
- ENSP00000445811
- ENSP00000461960
- ENSP00000461971
- ENSP00000462003
- ENSP00000462253
- ENSP00000462444
- ENSP00000462610
- ENSP00000462971
- ENSP00000463291
- ENSP00000463657
- ENSP00000463744
- ENSP00000463836
- ENSP00000463960
- ENSP00000464018
- ENSP00000464203
- ENSP00000464446
- ENSP00000354855
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for NFE2L1 (Nrf1)
- Cell Signaling Technology (CST) Antibodies for NFE2L1 (NFE2L1)
-
Custom Antibody ServicesOriGene Antibodies for NFE2L1
- Novus Biologicals Antibodies for NFE2L1
-
Abcam antibodies for NFE2L1
- Invitrogen Antibodies for NFE2L1
- GeneTex NFE2L1 antibody for NFE2L1
-
Santa Cruz Biotechnology (SCBT) Antibodies for NFE2L1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NFE2L1
- Origene Custom Protein Services for NFE2L1
- Novus Biologicals proteins for NFE2L1
- antibodies-online: Search results for 3 available NFE2L1 Proteins ranked by validation data
- Compare Top NFE2L1 Proteins
-
Quality Products:
- Search GeneTex for Proteins for NFE2L1
-
Abcam proteins for NFE2L1
Assay Products
- antibodies-online: Search results for 8 available NFE2L1 Elisa Kits ranked by validation data
- Compare Top NFE2L1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for NFE2L1 Gene
Domains & Families for NFE2L1 Gene
Gene Families for NFE2L1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Predicted secreted proteins
- Transcription factors
Protein Domains for NFE2L1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NFE2L1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q14494- Family:
-
- Belongs to the bZIP family. CNC subfamily.
Function for NFE2L1 Gene
Molecular function for NFE2L1 Gene
- GENATLAS Biochemistry:
- nuclear factor,erythroid derived 2-like 1,Capncollar (CNC) family of transcription factor,expressed in many tissues
- UniProtKB/Swiss-Prot Function:
- Activates erythroid-specific, globin gene expression.
Phenotypes From GWAS Catalog for NFE2L1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000976 | transcription regulatory region sequence-specific DNA binding | IBA | -- |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | IEA | -- |
GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding | IEA | -- |
GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | IEA | -- |
GO:0003677 | DNA binding | IEA | -- |
Phenotypes for NFE2L1 Gene
- MGI mutant phenotypes for NFE2L1:
- inferred from 5 alleles
- GenomeRNAi human phenotypes for NFE2L1:
Animal Models for NFE2L1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NFE2L1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NFE2L1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NFE2L1 gene
- Search ViGene Biosciences for NFE2L1
CRISPR Products
-
OriGene CRISPR knockouts for NFE2L1
- genomics-online: gRNA clones - Search results for 143 available NFE2L1 gene related products
- Overview of 143 available NFE2L1 gene related products
- Applied Biological Materials CRISPR for NFE2L1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NFE2L1
- GenScript: Design CRISPR guide RNA sequences for NFE2L1
miRNA for NFE2L1 Gene
- miRTarBase miRNAs that target NFE2L1
-
- hsa-mir-218-5p (MIRT003707)
- hsa-mir-342-5p (MIRT038213)
- hsa-mir-18a-3p (MIRT040917)
- hsa-mir-484 (MIRT042231)
- hsa-mir-324-3p (MIRT042976)
- hsa-mir-185-5p (MIRT045341)
- hsa-mir-30c-5p (MIRT047968)
- hsa-mir-99a-5p (MIRT048700)
- hsa-mir-92a-3p (MIRT049229)
- hsa-mir-1260b (MIRT052755)
- hsa-mir-6873-3p (MIRT655849)
- hsa-mir-6867-3p (MIRT655850)
- hsa-mir-6826-3p (MIRT655851)
- hsa-mir-421 (MIRT655852)
- hsa-mir-7158-5p (MIRT655853)
- hsa-mir-6817-3p (MIRT655854)
- hsa-mir-7110-3p (MIRT655855)
- hsa-mir-6845-3p (MIRT655856)
- hsa-mir-4685-3p (MIRT655857)
- hsa-mir-4287 (MIRT655858)
- hsa-mir-7113-3p (MIRT655859)
- hsa-mir-4469 (MIRT655860)
- hsa-mir-6795-3p (MIRT655861)
- hsa-mir-6887-3p (MIRT655862)
- hsa-mir-4709-5p (MIRT655863)
- hsa-mir-3912-5p (MIRT667217)
- hsa-mir-8057 (MIRT667218)
- hsa-mir-106a-3p (MIRT667219)
- hsa-mir-198 (MIRT667220)
- hsa-mir-4430 (MIRT667221)
- hsa-mir-3652 (MIRT667222)
- hsa-mir-24-3p (MIRT667223)
- hsa-mir-4284 (MIRT667224)
- hsa-mir-4634 (MIRT667225)
- hsa-mir-122-5p (MIRT667226)
- hsa-mir-504-3p (MIRT667227)
- hsa-mir-3135b (MIRT667228)
- hsa-mir-6812-3p (MIRT667229)
- hsa-mir-4673 (MIRT667230)
- hsa-mir-4645-5p (MIRT667231)
- hsa-mir-652-3p (MIRT667232)
- hsa-mir-454-3p (MIRT667233)
- hsa-mir-4295 (MIRT667234)
- hsa-mir-3666 (MIRT667235)
- hsa-mir-301b-3p (MIRT667236)
- hsa-mir-301a-3p (MIRT667237)
- hsa-mir-130b-3p (MIRT667238)
- hsa-mir-130a-3p (MIRT667239)
- hsa-mir-6791-5p (MIRT667240)
- hsa-mir-4292 (MIRT667241)
- hsa-mir-4308 (MIRT667242)
- hsa-mir-6892-3p (MIRT667243)
- hsa-mir-3607-5p (MIRT667244)
- hsa-mir-1207-5p (MIRT736044)
- hsa-mir-1226-5p (MIRT736133)
- hsa-mir-1249-5p (MIRT736445)
- hsa-mir-1273f (MIRT736805)
- hsa-mir-1909-3p (MIRT738359)
- hsa-mir-2682-5p (MIRT739420)
- hsa-mir-31-5p (MIRT740496)
- hsa-mir-34a-5p (MIRT741438)
- hsa-mir-34b-5p (MIRT741461)
- hsa-mir-34c-5p (MIRT741481)
- hsa-mir-3616-3p (MIRT741674)
- hsa-mir-3688-5p (MIRT742235)
- hsa-mir-3714 (MIRT742563)
- hsa-mir-4419a (MIRT744192)
- hsa-mir-4436b-3p (MIRT744464)
- hsa-mir-4470 (MIRT744947)
- hsa-mir-449a (MIRT745405)
- hsa-mir-449b-5p (MIRT745437)
- hsa-mir-449c-5p (MIRT745459)
- hsa-mir-4510 (MIRT745631)
- hsa-mir-4519 (MIRT745791)
- hsa-mir-4534 (MIRT746052)
- hsa-mir-4632-5p (MIRT746274)
- hsa-mir-4708-3p (MIRT747360)
- hsa-mir-4710 (MIRT747408)
- hsa-mir-4721 (MIRT747555)
- hsa-mir-4763-3p (MIRT748552)
- hsa-mir-5693 (MIRT751233)
- hsa-mir-6127 (MIRT752106)
- hsa-mir-6129 (MIRT752178)
- hsa-mir-6130 (MIRT752267)
- hsa-mir-6133 (MIRT752371)
- hsa-mir-6514-5p (MIRT753271)
- hsa-mir-6721-5p (MIRT753812)
- hsa-mir-6722-3p (MIRT753872)
- hsa-mir-6735-5p (MIRT754177)
- hsa-mir-6760-5p (MIRT754931)
- hsa-mir-6782-5p (MIRT755708)
- hsa-mir-6797-5p (MIRT756205)
- hsa-mir-6809-5p (MIRT756628)
- hsa-mir-6838-5p (MIRT757287)
- hsa-mir-6879-5p (MIRT758264)
- hsa-mir-7112-5p (MIRT759085)
- hsa-mir-7843-5p (MIRT759766)
- hsa-mir-8082 (MIRT760170)
- hsa-mir-3617-5p (MIRT766098)
- hsa-mir-4540 (MIRT770234)
- hsa-mir-548c-3p (MIRT774326)
- hsa-mir-548u (MIRT774542)
- hsa-mir-641 (MIRT776156)
- hsa-mir-6838-3p (MIRT780086)
- hsa-mir-7161-5p (MIRT781670)
Transcription Factor Targets for NFE2L1 Gene
miRNA Products
- Search ViGene Biosciences for NFE2L1
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for NFE2L1
- Browse OriGene Inhibitory RNA Products For NFE2L1
- genomics-online: shRNA clones - Search results for 143 available NFE2L1 gene related products
- Overview of 143 available NFE2L1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for NFE2L1 gene
Clone Products
- Sino Biological Human cDNA Clone for NFE2L1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NFE2L1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NFE2L1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for NFE2L1
- Applied Biological Materials Clones for NFE2L1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for NFE2L1
-
ViGene Biosciences adenoviral particle packaged cDNA for NFE2L1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NFE2L1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NFE2L1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology and HOMER Transcription for NFE2L1 Gene
Localization for NFE2L1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NFE2L1 Gene
- Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus.
- Cytosol (2)
- Nucleus (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | -- |
GO:0005737 | cytoplasm | IBA | -- |
GO:0005783 | endoplasmic reticulum | IEA | -- |
GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for NFE2L1 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Human Embryonic Stem Cell Pluripotency | ||
2 | ERK Signaling |
.58
|
.49
|
3 | PAK Pathway | ||
4 | TGF-Beta Pathway |
.51
|
|
5 | WNT Signaling |
Pathways by source for NFE2L1 Gene
7 Qiagen pathways for NFE2L1 Gene
Interacting Proteins for NFE2L1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0006357 | regulation of transcription by RNA polymerase II | IBA | -- |
GO:0006366 | transcription by RNA polymerase II | TAS | 9826775 |
GO:0006783 | heme biosynthetic process | TAS | 9501099 |
Transcripts for NFE2L1 Gene
mRNA/cDNA for NFE2L1 Gene
- (9) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (647) Selected AceView cDNA sequences:
- (23) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NFE2L1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for NFE2L1
- genomics-online: gRNA clones - Search results for 143 available NFE2L1 gene related products
- Overview of 143 available NFE2L1 gene related products
- Applied Biological Materials CRISPR for NFE2L1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NFE2L1
- GenScript: Design CRISPR guide RNA sequences for NFE2L1
miRNA Products
- Search ViGene Biosciences for NFE2L1
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for NFE2L1
- Browse OriGene Inhibitory RNA Products For NFE2L1
- genomics-online: shRNA clones - Search results for 143 available NFE2L1 gene related products
- Overview of 143 available NFE2L1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for NFE2L1 gene
Clone Products
- Sino Biological Human cDNA Clone for NFE2L1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NFE2L1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NFE2L1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for NFE2L1
- Applied Biological Materials Clones for NFE2L1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | · | 13d | · | 13e |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP8: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP9: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP10: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP11: | - | - |
Expression for NFE2L1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
mRNA differential expression in normal tissues according to GTEx for NFE2L1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NFE2L1 Gene
NURSA nuclear receptor signaling pathways regulating expression of NFE2L1 Gene:
NFE2L1SOURCE GeneReport for Unigene cluster for NFE2L1 Gene:
Hs.514284Evidence on tissue expression from TISSUES for NFE2L1 Gene
- Nervous system(4.7)
- Eye(4.6)
- Lung(3.6)
- Pancreas(3.2)
- Muscle(3.1)
- Heart(2.9)
- Intestine(2.3)
- Kidney(2.3)
- Skin(2.2)
Primer Products
-
OriGene qPCR primer pairs for NFE2L1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NFE2L1 Gene
Orthologs for NFE2L1 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | NFE2L1 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | NFE2L1 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | NFE2L1 34 33 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Nfe2l1 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Nfe2l1 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | NFE2L1 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | NFE2L1 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | NFE2L1 34 33 |
|
OneToOne | |
lizard (Anolis carolinensis) |
Reptilia | NFE2L1 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | nfe2l1 33 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | MGC68992 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | nfe2l1b 34 33 |
|
OneToOne | |
fruit fly (Drosophila melanogaster) |
Insecta | cnc 35 34 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for NFE2L1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for NFE2L1 Gene
(4) SIMAP similar genes for NFE2L1 Gene using alignment to 16 proteins:
Variants for NFE2L1 Gene
SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000035676 | -- | 48,059,834(+) | G/A | 3_prime_UTR_variant | |
rs1000230474 | -- | 48,048,335(+) | GGTAGCAGG/GG | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant | |
rs1000253068 | -- | 48,056,922(+) | G/A/T | intron_variant | |
rs1000489262 | -- | 48,060,664(+) | A/G | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
rs1000639718 | -- | 48,058,311(+) | C/T | coding_sequence_variant, missense_variant |
Additional Variant Information for NFE2L1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NFE2L1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NFE2L1 Gene
Disorders for NFE2L1 Gene
Additional Disease Information for NFE2L1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for NFE2L1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NFE2L1 Gene
Publications for NFE2L1 Gene
- Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. (PMID: 8248256) Chan JY … Kan YW (Proceedings of the National Academy of Sciences of the United States of America 1993) 2 3 4 22 58
- Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function. (PMID: 16687406) Wang W … Chan JY (The Journal of biological chemistry 2006) 3 4 22 58
- Cloning and functional characterization of LCR-F1: a bZIP transcription factor that activates erythroid-specific, human globin gene expression. (PMID: 8036168) Caterina JJ … Townes TM (Nucleic acids research 1994) 3 4 22 58
- Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells. (PMID: 20385086) Radhakrishnan SK … Deshaies RJ (Molecular cell 2010) 3 22 58
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PMID: 20935630) Speliotes EK … Loos RJ (Nature genetics 2010) 3 44 58
Products for NFE2L1 Gene
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- Custom Antibody ServicesOriGene Antibodies for NFE2L1
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- Invitrogen Antibodies for NFE2L1
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- Mammalian expression: PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
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- Addgene plasmids for NFE2L1
- antibodies-online: Search results for 46 available NFE2L1 Antibodies ranked by validation data
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- antibodies-online: Search results for 3 available NFE2L1 Proteins ranked by validation data
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- Quality Products:
- GeneTex NFE2L1 antibody for NFE2L1
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- ViGene Biosciences adenoviral particle packaged cDNA for NFE2L1 gene
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- Search ViGene Biosciences for NFE2L1
- Santa Cruz Biotechnology (SCBT) Antibodies for NFE2L1
- Search Santa Cruz Biotechnology (SCBT) for NFE2L1 siRNA/shRNA
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- Horizon Cell Lines for NFE2L1
- genomics-online: cdna clones - Search results for 143 available NFE2L1 gene related products
- Overview of 143 available NFE2L1 gene related products
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- Overview of 143 available NFE2L1 gene related products
- genomics-online: shRNA clones - Search results for 143 available NFE2L1 gene related products
- Overview of 143 available NFE2L1 gene related products
Sources for NFE2L1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
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- (114) diseasecard
- (115) NIH Rare Diseases
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- (125) NCBI Bookshelf
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- (133) ENCODE
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- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
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- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew