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Aliases for MT-TS1 Gene

Subcategory (RNA class) for MT-TS1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for MT-TS1 Gene

  • Mitochondrially Encoded TRNA Serine 1 (UCN) 2
  • TRNA Serine 1 (UCN) 2
  • TRNS1 3
  • MTTS1 3
  • TRNA 3

External Ids for MT-TS1 Gene

Previous HGNC Symbols for MT-TS1 Gene

  • MTTS1

Previous GeneCards Identifiers for MT-TS1 Gene

  • GC00U921612

Summaries for MT-TS1 Gene

GeneCards Summary for MT-TS1 Gene

MT-TS1 (Mitochondrially Encoded TRNA Serine 1 (UCN)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TS1 include melas, mt-ts1-related and mt-ts1-related hearing loss and deafness. Among its related pathways are tRNA Aminoacylation.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TS1 Gene

Genomics for MT-TS1 Gene

Genomic Location for MT-TS1 Gene

7,446 bp from pter
7,514 bp from pter
69 bases
Minus strand

Genomic View for MT-TS1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TS1 Gene

No data available for Regulatory Elements for MT-TS1 Gene

Proteins for MT-TS1 Gene

Post-translational modifications for MT-TS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TS1 Gene

Domains & Families for MT-TS1 Gene

Gene Families for MT-TS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TS1 Gene

Function for MT-TS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TS1 Gene

Localization for MT-TS1 Gene

Subcellular locations from

Jensen Localization Image for MT-TS1 Gene COMPARTMENTS Subcellular localization image for MT-TS1 gene
Compartment Confidence
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT-TS1 Gene

Pathways & Interactions for MT-TS1 Gene

SuperPathways for MT-TS1 Gene

Superpath Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TS1: view

Pathways by source for MT-TS1 Gene

1 KEGG pathway for MT-TS1 Gene

Interacting Proteins for MT-TS1 Gene

Gene Ontology (GO) - Biological Process for MT-TS1 Gene


No data available for SIGNOR curated interactions for MT-TS1 Gene

Drugs & Compounds for MT-TS1 Gene

No Compound Related Data Available

Transcripts for MT-TS1 Gene

mRNA/cDNA for MT-TS1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TS1 Gene

No ASD Table

Relevant External Links for MT-TS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MT-TS1 Gene

mRNA expression in normal human tissues for MT-TS1 Gene

genes like me logo Genes that share expression patterns with MT-TS1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MT-TS1 Gene

Orthologs for MT-TS1 Gene

Evolution for MT-TS1 Gene

Gene Tree for MT-TS1 (if available)
Gene Tree for MT-TS1 (if available)

No data available for Orthologs for MT-TS1 Gene

Paralogs for MT-TS1 Gene

No data available for Paralogs for MT-TS1 Gene

Variants for MT-TS1 Gene

Relevant External Links for MT-TS1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TS1 Gene

Disorders for MT-TS1 Gene

MalaCards: The human disease database

(12) MalaCards diseases for MT-TS1 Gene - From: ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
melas, mt-ts1-related
  • melas, mtts1-related
mt-ts1-related hearing loss and deafness
maternally-inherited progressive external ophthalmoplegia
  • maternally-inherited cpeo
nonsyndromic hearing loss and deafness, mitochondrial
  • nonsyndromic deafness and hearing loss, maternally-inherited
mitochondrial non-syndromic sensorineural deafness with susceptibility to aminoglycoside exposure
  • mitochondrial isolated neurosensory deafness with susceptibility to aminoglycoside exposure
- elite association

Relevant External Links for MT-TS1

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with MT-TS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TS1 Gene

Publications for MT-TS1 Gene

  1. Fatal neonatal lactic acidosis caused by a novel de novo mitochondrial G7453A tRNA-Serine ((UCN)) mutation. (PMID: 22453297) GAPtz A. … Suomalainen A. (Pediatr. Res. 2012) 67
  2. The search of a genetic basis for noise-induced hearing loss (NIHL). (PMID: 20812880) Abreu-Silva R.S. … Mingroni-Netto R.C. (Ann. Hum. Biol. 2011) 67
  3. Genotyping with a 198 mutation arrayed primer extension array for hereditary hearing loss: assessment of its diagnostic value for medical practice. (PMID: 20668687) Rodriguez-Paris J. … Schrijver I. (PLoS ONE 2010) 67
  4. Extensive screening system using suspension array technology to detect mitochondrial DNA point mutations. (PMID: 20064630) Nishigaki Y. … Tanaka M. (Mitochondrion 2010) 67
  5. Role of the mitochondrial mutations, m.827A>G and the novel m.7462C>T, in the origin of hearing loss. (PMID: 20722495) Uehara D.T. … Mingroni-Netto R.C. (Genet Test Mol Biomarkers 2010) 67

Products for MT-TS1 Gene

Sources for MT-TS1 Gene

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