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Aliases for MT-TS1 Gene

Subcategory (RNA class) for MT-TS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for MT-TS1 Gene

  • Mitochondrially Encoded TRNA Serine 1 (UCN) 2 5
  • TRNA Serine 1 (UCN) 2
  • TRNS1 3
  • MTTS1 3
  • TRNA 3

External Ids for MT-TS1 Gene

Previous HGNC Symbols for MT-TS1 Gene

  • MTTS1

Previous GeneCards Identifiers for MT-TS1 Gene

  • GC00U921612

Summaries for MT-TS1 Gene

GeneCards Summary for MT-TS1 Gene

MT-TS1 (Mitochondrially Encoded TRNA Serine 1 (UCN)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TS1 include maternally-inherited progressive external ophthalmoplegia and mitochondrial non-syndromic sensorineural deafness. Among its related pathways are tRNA Aminoacylation.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TS1 Gene

Genomics for MT-TS1 Gene

Genomic Location for MT-TS1 Gene

Chromosome:
MT
Start:
7,446 bp from pter
End:
7,514 bp from pter
Size:
69 bases
Orientation:
Minus strand

Genomic View for MT-TS1 Gene

Genes around MT-TS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TS1 Gene

No data available for Regulatory Elements for MT-TS1 Gene

Proteins for MT-TS1 Gene

Post-translational modifications for MT-TS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TS1 Gene

Domains & Families for MT-TS1 Gene

Gene Families for MT-TS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TS1 Gene

Function for MT-TS1 Gene

Human Phenotype Ontology for MT-TS1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TS1 Gene

Localization for MT-TS1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MT-TS1 Gene COMPARTMENTS Subcellular localization image for MT-TS1 gene
Compartment Confidence
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT-TS1 Gene

Pathways & Interactions for MT-TS1 Gene

SuperPathways for MT-TS1 Gene

Superpath Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TS1: view

Pathways by source for MT-TS1 Gene

1 KEGG pathway for MT-TS1 Gene

Interacting Proteins for MT-TS1 Gene

Gene Ontology (GO) - Biological Process for MT-TS1 Gene

None

No data available for SIGNOR curated interactions for MT-TS1 Gene

Drugs & Compounds for MT-TS1 Gene

No Compound Related Data Available

Transcripts for MT-TS1 Gene

mRNA/cDNA for MT-TS1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TS1 Gene

No ASD Table

Relevant External Links for MT-TS1 Gene

GeneLoc Exon Structure for
MT-TS1
ECgene alternative splicing isoforms for
MT-TS1

Expression for MT-TS1 Gene

mRNA expression in normal human tissues for MT-TS1 Gene

genes like me logo Genes that share expression patterns with MT-TS1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MT-TS1 Gene

Orthologs for MT-TS1 Gene

Evolution for MT-TS1 Gene

ENSEMBL:
Gene Tree for MT-TS1 (if available)
TreeFam:
Gene Tree for MT-TS1 (if available)

No data available for Orthologs for MT-TS1 Gene

Paralogs for MT-TS1 Gene

No data available for Paralogs for MT-TS1 Gene

Variants for MT-TS1 Gene

Relevant External Links for MT-TS1 Gene

HapMap Linkage Disequilibrium report
MT-TS1
Human Gene Mutation Database (HGMD)
MT-TS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TS1 Gene

Disorders for MT-TS1 Gene

MalaCards: The human disease database

(12) MalaCards diseases for MT-TS1 Gene - From: GeneTests, Orphanet, and GeneCards

Disorder Aliases PubMed IDs
maternally-inherited progressive external ophthalmoplegia
  • maternally-inherited cpeo
mitochondrial non-syndromic sensorineural deafness
  • isolated mitochondrial neurosensory deafness
keratoderma, palmoplantar, with deafness
  • keratoderma palmoplantar deafness
merrf syndrome
  • fukuhara syndrome
melas syndrome
  • mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MT-TS1

Genetic Association Database (GAD)
MT-TS1
genes like me logo Genes that share disorders with MT-TS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TS1 Gene

Publications for MT-TS1 Gene

  1. Mutational analysis of the mitochondrial 12S rRNA and tRNASer(UCN) genes in Tunisian patients with nonsyndromic hearing loss. (PMID: 16406239) Mkaouar-Rebai E. … Fakhfakh F. (Biochem. Biophys. Res. Commun. 2006) 3 48 67
  2. Fatal neonatal lactic acidosis caused by a novel de novo mitochondrial G7453A tRNA-Serine ((UCN)) mutation. (PMID: 22453297) GAPtz A. … Suomalainen A. (Pediatr. Res. 2012) 3
  3. The search of a genetic basis for noise-induced hearing loss (NIHL). (PMID: 20812880) Abreu-Silva R.S. … Mingroni-Netto R.C. (Ann. Hum. Biol. 2011) 3
  4. Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer. (PMID: 19527772) Hung W.Y. … Lee H.C. (Biochim. Biophys. Acta 2010) 3
  5. Extensive screening system using suspension array technology to detect mitochondrial DNA point mutations. (PMID: 20064630) Nishigaki Y. … Tanaka M. (Mitochondrion 2010) 3

Products for MT-TS1 Gene

Sources for MT-TS1 Gene

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