Aliases for MLLT4 Gene
External Ids for MLLT4 Gene
Previous GeneCards Identifiers for MLLT4 Gene
This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]
GeneCards Summary for MLLT4 Gene
MLLT4 (Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 4) is a Protein Coding gene. Diseases associated with MLLT4 include lymphoblastic leukemia and leukemia. Among its related pathways are Ras signaling pathway and Ras signaling pathway. GO annotations related to this gene include protein C-terminus binding and cell adhesion molecule binding. An important paralog of this gene is PPP1R9A.
UniProtKB/Swiss-Prot for MLLT4 Gene
Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton