Aliases for STS Gene
External Ids for STS Gene
Previous Symbols for STS Gene
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq, Jul 2008]
GeneCards Summary for STS Gene
STS (Steroid Sulfatase (Microsomal), Isozyme S) is a Protein Coding gene. Diseases associated with STS include ichthyosis, x-linked and pre-descemet corneal dystrophy. Among its related pathways are PTM- gamma carboxylation, hypusine formation and arylsulfatase activation and PTM- gamma carboxylation, hypusine formation and arylsulfatase activation. GO annotations related to this gene include sulfuric ester hydrolase activity and steryl-sulfatase activity. An important paralog of this gene is ARSJ.
UniProtKB/Swiss-Prot for STS Gene
Conversion of sulfated steroid precursors to estrogens during pregnancy