Aliases for LYZ Gene
External Ids for LYZ Gene
This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]
GeneCards Summary for LYZ Gene
LYZ (Lysozyme) is a Protein Coding gene. Diseases associated with LYZ include malignant fibroxanthoma and reticulosarcoma. Among its related pathways are Disease and RNA Polymerase I Promoter Opening. GO annotations related to this gene include identical protein binding and lysozyme activity. An important paralog of this gene is SPACA5B.
UniProtKB/Swiss-Prot for LYZ Gene
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents