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Aliases for LIPE Gene

Aliases for LIPE Gene

  • Lipase E, Hormone Sensitive Type 2 3 5
  • Lipase, Hormone-Sensitive 2 3
  • EC 3.1.1.79 4 58
  • HSL 3 4
  • Hormone-Sensitive Lipase Testicular Isoform 3
  • Hormone-Sensitive Lipase 3
  • AOMS4 3
  • FPLD6 3
  • LHS 3

External Ids for LIPE Gene

Previous GeneCards Identifiers for LIPE Gene

  • GC19M043552
  • GC19M043297
  • GC19M047581
  • GC19M047597
  • GC19M042906
  • GC19M039335

Summaries for LIPE Gene

Entrez Gene Summary for LIPE Gene

  • The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008]

GeneCards Summary for LIPE Gene

LIPE (Lipase E, Hormone Sensitive Type) is a Protein Coding gene. Diseases associated with LIPE include Lipodystrophy, Familial Partial, Type 6 and Lipe-Related Familial Partial Lipodystrophy. Among its related pathways are Metabolism and triacylglycerol biosynthesis. GO annotations related to this gene include protein kinase binding and triglyceride lipase activity.

UniProtKB/Swiss-Prot for LIPE Gene

  • In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

Gene Wiki entry for LIPE Gene

Additional gene information for LIPE Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LIPE Gene

Genomics for LIPE Gene

Regulatory Elements for LIPE Gene

Enhancers for LIPE Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H042449 1.9 FANTOM5 Ensembl ENCODE dbSUPER 22.1 -22.9 -22904 1 PKNOX1 FOXA2 MLX ARNT ARID4B DMAP1 YY1 SLC30A9 ZNF143 ZNF207 LIPE CEACAMP1 CEACAMP10 PSG6 ZNF526 RNU4-60P PSG8 CD177 CEACAM1 CXCL17
GH19H042267 1.9 FANTOM5 ENCODE dbSUPER 6.9 +156.5 156539 6 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 YBX1 ZBTB7B YY1 ZNF526 ZNF574 CCDC97 DEDD2 MEGF8 CEACAM3 PAFAH1B3 PRR19 GSK3A TMEM145
GH19H042183 1.3 Ensembl ENCODE dbSUPER 10 +242.5 242534 1 HDGF CTCF RB1 RAD21 TEAD3 ZNF766 ZNF316 CTBP1 SMC3 ZNF143 LOC100505622 ZNF526 DEDD2 LIPE-AS1 LIPE GRIK5 POU2F2 ENSG00000259436
GH19H042419 1.8 FANTOM5 Ensembl ENCODE dbSUPER 6 +4.9 4897 5 HDGF PKNOX1 FOXA2 ATF1 ARID4B SIN3A ZNF2 BRCA1 ZNF143 ATF7 CIC LIPE CD177 ENSG00000268605 LIPE-AS1 LOC101930071
GH19H042363 0.9 Ensembl ENCODE 11 +63.6 63582 1 PKNOX1 ZNF687 ZNF114 ELF1 ZNF592 ZNF169 KLF9 MLLT1 RUNX3 MGA MEGF8 CNFN LIPE-AS1 LIPE GSK3A GC19P042378 MIR8077 PIR47672
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LIPE on UCSC Golden Path with GeneCards custom track

Genomic Location for LIPE Gene

Chromosome:
19
Start:
42,401,507 bp from pter
End:
42,427,426 bp from pter
Size:
25,920 bases
Orientation:
Minus strand

Genomic View for LIPE Gene

Genes around LIPE on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LIPE Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LIPE Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LIPE Gene

Proteins for LIPE Gene

  • Protein details for LIPE Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q05469-LIPS_HUMAN
    Recommended name:
    Hormone-sensitive lipase
    Protein Accession:
    Q05469
    Secondary Accessions:
    • Q3LRT2
    • Q6NSL7

    Protein attributes for LIPE Gene

    Size:
    1076 amino acids
    Molecular mass:
    116598 Da
    Quaternary structure:
    • Interacts with CAVIN1 in the adipocyte cytoplasm (PubMed:17026959). Interacts with PLIN5 (By similarity).

    Alternative splice isoforms for LIPE Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LIPE Gene

Selected DME Specific Peptides for LIPE Gene

Q05469:
  • QNLDVHFWKAFWNITE
  • ASPSRLLSLMD
  • HGGGFVAQTS
  • PSTPSDVNF
  • ETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFR
  • GDSAGGNL
  • LTVTISPPLAHTGP
  • SIDYSLAPEAPFPRALEECF
  • MDLRTMTQSLV
  • LLPLSVLSKCVS
  • YYAQRLL
  • SHNLAELEAYLAALTQLRA
  • MRRSVSEAALAQP
  • AFFSSQGPGETA

Post-translational modifications for LIPE Gene

  • Phosphorylation by AMPK may block translocation to lipid droplets.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • R&D Systems Antibodies for LIPE (Hormone-sensitive Lipase/HSL)
  • Cell Signaling Technology (CST) Antibodies for LIPE (HSL)
  • Santa Cruz Biotechnology (SCBT) Antibodies for LIPE

Domains & Families for LIPE Gene

Gene Families for LIPE Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for LIPE Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q05469

UniProtKB/Swiss-Prot:

LIPS_HUMAN :
  • Belongs to the GDXG lipolytic enzyme family.
Family:
  • Belongs to the GDXG lipolytic enzyme family.
genes like me logo Genes that share domains with LIPE: view

Function for LIPE Gene

Molecular function for LIPE Gene

GENATLAS Biochemistry:
lipase,hormone sensitive with two isoforms expressed in adipose tissue (HSLadi),testis (HSLtes),associated with obesity and non insulin dependent diabetes
UniProtKB/Swiss-Prot CatalyticActivity:
Diacylglycerol + H(2)O = monoacylglycerol + a carboxylate.
UniProtKB/Swiss-Prot CatalyticActivity:
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
UniProtKB/Swiss-Prot CatalyticActivity:
Monoacylglycerol + H(2)O = glycerol + a carboxylate.
UniProtKB/Swiss-Prot EnzymeRegulation:
Rapidly activated by cAMP-dependent phosphorylation under the influence of catecholamines. Dephosphorylation and inactivation are controlled by insulin.
UniProtKB/Swiss-Prot Function:
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

Enzyme Numbers (IUBMB) for LIPE Gene

Gene Ontology (GO) - Molecular Function for LIPE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004806 triglyceride lipase activity IEA --
GO:0005515 protein binding IPI 17026959
GO:0016298 lipase activity IEA --
GO:0016787 hydrolase activity IEA --
GO:0019901 protein kinase binding IEA --
genes like me logo Genes that share ontologies with LIPE: view
genes like me logo Genes that share phenotypes with LIPE: view

Human Phenotype Ontology for LIPE Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for LIPE Gene

MGI Knock Outs for LIPE:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for LIPE
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Phenotypes From GWAS Catalog , miRNA , Transcription Factor Targets and HOMER Transcription for LIPE Gene

Localization for LIPE Gene

Subcellular locations from UniProtKB/Swiss-Prot for LIPE Gene

Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LIPE gene
Compartment Confidence
plasma membrane 5
cytosol 5
nucleus 3
extracellular 2
mitochondrion 2
peroxisome 2
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for LIPE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005811 lipid particle ISS,IEA --
GO:0005829 cytosol IDA --
GO:0005886 plasma membrane IEA --
GO:0005901 caveola IEA --
genes like me logo Genes that share ontologies with LIPE: view

Pathways & Interactions for LIPE Gene

genes like me logo Genes that share pathways with LIPE: view

UniProtKB/Swiss-Prot Q05469-LIPS_HUMAN

  • Pathway: Glycerolipid metabolism; triacylglycerol degradation.

SIGNOR curated interactions for LIPE Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for LIPE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation TAS 3420405
GO:0006629 lipid metabolic process IEA --
GO:0008152 metabolic process IEA --
GO:0008202 steroid metabolic process IEA --
GO:0008203 cholesterol metabolic process IEA --
genes like me logo Genes that share ontologies with LIPE: view

Drugs & Compounds for LIPE Gene

(36) Drugs for LIPE Gene - From: DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Glycerol Approved, Investigational Pharma 253
Water Approved Pharma 0
cyclic amp Experimental Pharma 0
Myristic acid Experimental Pharma 0
Palmitic Acid Experimental Pharma Full agonist, Agonist 22

(99) Additional Compounds for LIPE Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
2-Arachidonylglycerol
  • (5Z,8Z,11Z,14Z)-2-hydroxy-1-(hydroxymethyl)ethyl ester 5,8,11,14-Eicosatetraenoate
  • (5Z,8Z,11Z,14Z)-2-hydroxy-1-(hydroxymethyl)ethyl ester 5,8,11,14-Eicosatetraenoic acid
  • (all-Z)-2-hydroxy-1-(hydroxymethyl)ethyl ester 5,8,11,14-Eicosatetraenoate
  • (all-Z)-2-hydroxy-1-(hydroxymethyl)ethyl ester 5,8,11,14-Eicosatetraenoic acid
  • 1-Monoacylglyceride
53847-30-6
Arachidic acid
  • Arachate
  • Arachic acid
  • Arachidate
  • Arachidic acid
  • Eicosanoate
506-30-9
Diglycerides Group A
  • 1,2-Dimyristoyl-rac-glycerol
  • DAG(14:0/14:0)
  • DAG(28:0)
  • DG(14:0/14:0)
  • DG(28:0)
Diglycerides Group B
  • 1-Palmitoleoyl-2-arachidonyl-sn-glycerol
  • DAG(16:1/20:0)
  • DAG(16:1n7/20:0)
  • DAG(16:1w7/20:0)
  • DAG(36:1)
Diglycerides Group C
  • 1-Myristoyl-3-behenoyl-sn-glycerol
  • 1-Tetradecanoyl-3-docosanoyl-sn-glycerol
  • DAG(14:0/0:0/22:0)
  • DAG(36:0)
  • DG(36:0)
genes like me logo Genes that share compounds with LIPE: view

Transcripts for LIPE Gene

Unigene Clusters for LIPE Gene

Lipase, hormone-sensitive:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for LIPE
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for LIPE Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b · 13c ^ 14
SP1: - - -
SP2: -
SP3: -
SP4:
SP5:
SP6: - - - -
SP7:
SP8: - - - -
SP9: - - -
SP10: -

Relevant External Links for LIPE Gene

GeneLoc Exon Structure for
LIPE
ECgene alternative splicing isoforms for
LIPE

Expression for LIPE Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LIPE Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for LIPE Gene

This gene is overexpressed in Adipose - Subcutaneous (x14.8), Adipose - Visceral (Omentum) (x11.2), and Breast - Mammary Tissue (x7.7).

Protein differential expression in normal tissues from HIPED for LIPE Gene

This gene is overexpressed in Adipocyte (47.7) and Nasopharynx (19.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for LIPE Gene



NURSA nuclear receptor signaling pathways regulating expression of LIPE Gene:

LIPE

SOURCE GeneReport for Unigene cluster for LIPE Gene:

Hs.656980

Evidence on tissue expression from TISSUES for LIPE Gene

  • Nervous system(3.7)
  • Muscle(2.5)
  • Blood(2.2)
  • Adrenal gland(2.1)
  • Liver(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for LIPE Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • reproductive
  • skeletal muscle
  • skeleton
Organs:
Head and neck:
  • ear
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • neck
  • skull
Thorax:
  • chest wall
  • clavicle
  • heart
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • intestine
  • liver
  • pancreas
  • small intestine
Pelvis:
  • ovary
  • pelvis
  • uterus
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • skin
  • spinal column
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with LIPE: view

Primer Products

No data available for Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for LIPE Gene

Orthologs for LIPE Gene

This gene was present in the common ancestor of animals.

Orthologs for LIPE Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LIPE 33 34
  • 99.26 (n)
cow
(Bos Taurus)
Mammalia LIPE 33
  • 86.17 (n)
HSL 34
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LIPE 33
  • 83.98 (n)
HSL 34
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Lipe 16 34 33
  • 81.96 (n)
rat
(Rattus norvegicus)
Mammalia Lipe 33
  • 78.08 (n)
oppossum
(Monodelphis domestica)
Mammalia LIPE 34
  • 53 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia LIPE 34
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia LIPE 34
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia lipe 33
  • 62.34 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.18619 33
zebrafish
(Danio rerio)
Actinopterygii lipeb 34 33
  • 61.53 (n)
OneToMany
lipea 34
  • 53 (a)
OneToMany
Dr.14982 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13588 33
fruit fly
(Drosophila melanogaster)
Insecta CG11055 34 35
  • 28 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C46C11.1 35
  • 33 (a)
hosl-1 34
  • 24 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 51 (a)
OneToMany
CSA.8706 34
  • 26 (a)
OneToMany
Species where no ortholog for LIPE was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for LIPE Gene

ENSEMBL:
Gene Tree for LIPE (if available)
TreeFam:
Gene Tree for LIPE (if available)

Paralogs for LIPE Gene

No data available for Paralogs for LIPE Gene

Variants for LIPE Gene

Sequence variations from dbSNP and Humsavar for LIPE Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
VAR_036539 A breast cancer sample
rs587777699 Pathogenic 42,401,822(+) GTCGC(-/CCCCCGCAGCCCCCGTCTA)CCCCC intron-variant, reference, frameshift-variant
rs1000020124 -- 42,428,236(+) AGTCA(C/T)AAATA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1000082000 -- 42,417,757(+) GGCTC(A/G)TACTT intron-variant
rs1000256612 -- 42,422,547(+) GGGAA(A/G)CAATG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for LIPE Gene

Variant ID Type Subtype PubMed ID
dgv6460n54 CNV loss 21841781
esv2422471 CNV deletion 17116639
nsv520239 CNV loss 19592680
nsv522854 CNV gain 19592680
nsv526186 CNV gain 19592680
nsv579632 CNV gain 21841781
nsv579633 CNV loss 21841781
nsv953584 CNV deletion 24416366

Variation tolerance for LIPE Gene

Residual Variation Intolerance Score: 83.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.72; 73.20% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LIPE Gene

Human Gene Mutation Database (HGMD)
LIPE
SNPedia medical, phenotypic, and genealogical associations of SNPs for
LIPE

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LIPE Gene

Disorders for LIPE Gene

MalaCards: The human disease database

(9) MalaCards diseases for LIPE Gene - From: HGMD, OMIM, ClinVar, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
lipodystrophy, familial partial, type 6
  • lipe-related familial partial lipodystrophy
lipe-related familial partial lipodystrophy
  • fpld6
lipodystrophy
hyperlipidemia, familial combined
  • combined hyperlipidemia, familial
lipomatosis, multiple symmetric
  • multiple symmetric lipomatosis
- elite association - COSMIC cancer census association via MalaCards
Search LIPE in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

LIPS_HUMAN
  • Lipodystrophy, familial partial, 6 (FPLD6) [MIM:615980]: A form of lipodystrophy characterized by abnormal subcutaneous fat distribution. Affected individuals have increased visceral fat, impaired lipolysis, dyslipidemia, hepatic steatosis, systemic insulin resistance, and diabetes. Some patients manifest muscular dystrophy. {ECO:0000269 PubMed:24848981}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for LIPE

Genetic Association Database (GAD)
LIPE
Human Genome Epidemiology (HuGE) Navigator
LIPE
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LIPE
genes like me logo Genes that share disorders with LIPE: view

No data available for Genatlas for LIPE Gene

Publications for LIPE Gene

  1. Gene organization and primary structure of human hormone-sensitive lipase: possible significance of a sequence homology with a lipase of Moraxella TA144, an antarctic bacterium. (PMID: 8506334) Langin D … Holm C (Proceedings of the National Academy of Sciences of the United States of America 1993) 2 3 4 22 60
  2. Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene. (PMID: 18249203) Jocken JW … Saris WH (Metabolism: clinical and experimental 2008) 3 22 45 60
  3. The combination of ApoCIII, hepatic lipase and hormono sensitive lipase gene polymorphisms suggests an association with susceptibility to gestational hypertension. (PMID: 17318300) Bernard N … Giguère Y (Journal of human genetics 2007) 3 22 45 60
  4. Association and insulin regulated translocation of hormone-sensitive lipase with PTRF. (PMID: 17026959) Aboulaich N … Strålfors P (Biochemical and biophysical research communications 2006) 3 4 22 60
  5. Investigation into the role of the hormone sensitive lipase -60C>G promoter variant in morbid obesity. (PMID: 15871848) Talmud PJ … Beisiegel U (Nutrition, metabolism, and cardiovascular diseases : NMCD 2005) 3 22 45 60

Products for LIPE Gene

Sources for LIPE Gene

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