Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR6Y1 Gene

Aliases for OR6Y1 Gene

  • Olfactory Receptor, Family 6, Subfamily Y, Member 1 2 3
  • Olfactory Receptor OR1-11 3 4
  • Olfactory Receptor 6Y2 3 4
  • OR6Y2 3 4
  • Olfactory Receptor 6Y1 3
  • OR1-11 3

External Ids for OR6Y1 Gene

Previous Symbols for OR6Y1 Gene

  • OR6Y2

Summaries for OR6Y1 Gene

Entrez Gene Summary for OR6Y1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR6Y1 Gene

OR6Y1 (Olfactory Receptor, Family 6, Subfamily Y, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR11L1.

UniProtKB/Swiss-Prot for OR6Y1 Gene

  • Odorant receptor.

Gene Wiki entry for OR6Y1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR6Y1 Gene

Genomics for OR6Y1 Gene

Genomic Location for OR6Y1 Gene

Start:
158,547,128 bp from pter
End:
158,548,105 bp from pter
Size:
978 bases
Orientation:
Minus strand

Genomic View for OR6Y1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR6Y1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR6Y1 Gene

Regulatory Elements for OR6Y1 Gene

Proteins for OR6Y1 Gene

  • Protein details for OR6Y1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGX8-OR6Y1_HUMAN
    Recommended name:
    Olfactory receptor 6Y1
    Protein Accession:
    Q8NGX8
    Secondary Accessions:
    • Q6IFS0

    Protein attributes for OR6Y1 Gene

    Size:
    325 amino acids
    Molecular mass:
    36636 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR6Y1 Gene

Proteomics data for OR6Y1 Gene at MOPED

Post-translational modifications for OR6Y1 Gene

  • Glycosylation at Asn10 and Asn191

Other Protein References for OR6Y1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR6Y1 Gene

Domains for OR6Y1 Gene

Gene Families for OR6Y1 Gene

HGNC:
  • OR6 :GPCR / Class A : Olfactory receptors

Protein Domains for OR6Y1 Gene

Suggested Antigen Peptide Sequences for OR6Y1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGX8

UniProtKB/Swiss-Prot:

OR6Y1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGX8
genes like me logo Genes that share domains with OR6Y1: view

Function for OR6Y1 Gene

Molecular function for OR6Y1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR6Y1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR6Y1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR6Y1 Gene

Localization for OR6Y1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR6Y1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR6Y1 Gene COMPARTMENTS Subcellular localization image for OR6Y1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR6Y1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR6Y1: view

Pathways for OR6Y1 Gene

genes like me logo Genes that share pathways with OR6Y1: view

Pathways by source for OR6Y1 Gene

Interacting Proteins for OR6Y1 Gene

Gene Ontology (GO) - Biological Process for OR6Y1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR6Y1: view

Transcripts for OR6Y1 Gene

mRNA/cDNA for OR6Y1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR6Y1 Gene

No ASD Table

Relevant External Links for OR6Y1 Gene

GeneLoc Exon Structure for
OR6Y1
ECgene alternative splicing isoforms for
OR6Y1

Expression for OR6Y1 Gene

mRNA expression in normal human tissues for OR6Y1 Gene

SOURCE GeneReport for Unigene cluster for OR6Y1 Gene Hs.553780

genes like me logo Genes that share expressions with OR6Y1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR6Y1 Gene

Orthologs for OR6Y1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR6Y1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC469529 35
  • 98.67 (n)
  • 97.23 (a)
OR6Y1 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR6Y1 35
  • 85.61 (n)
  • 85.09 (a)
OR6Y1 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR6Y1 35
  • 85.86 (n)
  • 86.69 (a)
OR6Y1 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr220 35
  • 84.37 (n)
  • 87.19 (a)
Olfr220 16
Olfr220 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OR6Y1 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr1602 35
  • 84.21 (n)
  • 87.38 (a)
lizard
(Anolis carolinensis)
Reptilia OR6Y1 36
  • 65 (a)
OneToOne
Species with no ortholog for OR6Y1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR6Y1 Gene

ENSEMBL:
Gene Tree for OR6Y1 (if available)
TreeFam:
Gene Tree for OR6Y1 (if available)

Paralogs for OR6Y1 Gene

Paralogs for OR6Y1 Gene

Selected SIMAP similar genes for OR6Y1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR6Y1 Gene

genes like me logo Genes that share paralogs with OR6Y1: view

Variants for OR6Y1 Gene

Sequence variations from dbSNP and Humsavar for OR6Y1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs9804152 -- 158,549,149(+) AAAAC(C/T)GTAAT upstream-variant-2KB
rs10797025 -- 158,549,735(+) GCTCA(C/T)TGCAG upstream-variant-2KB
rs10797026 -- 158,549,920(+) TACTA(C/T)ATCAC upstream-variant-2KB
rs11805617 -- 158,547,045(+) GATTG(A/G)GGGAT downstream-variant-500B
rs16840314 -- 158,547,563(+) AAGTA(A/G)TGATT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for OR6Y1 Gene

Variant ID Type Subtype PubMed ID
nsv470743 CNV Loss 18288195
dgv15n17 CNV Loss 16327808
esv2667471 CNV Deletion 23128226
esv2422163 CNV Deletion 20811451
nsv442095 CNV CNV 18776908
dgv40n27 CNV Loss 19166990
nsv515774 CNV Loss 19592680

Relevant External Links for OR6Y1 Gene

HapMap Linkage Disequilibrium report
OR6Y1
Human Gene Mutation Database (HGMD)
OR6Y1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR6Y1 Gene

Disorders for OR6Y1 Gene

No disorders were found for OR6Y1 Gene.

No data available for UniProtKB/Swiss-Prot for OR6Y1 Gene

Publications for OR6Y1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Seventy-five genetic loci influencing the human red blood cell. (PMID: 23222517) van der Harst P. … Chambers J.C. (Nature 2012) 3

Products for OR6Y1 Gene

Sources for OR6Y1 Gene

Back to Top

Content