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Aliases for OR5D16 Gene

Aliases for OR5D16 Gene

  • Olfactory Receptor, Family 5, Subfamily D, Member 16 2 3
  • Olfactory Receptor OR11-154 3 4
  • Olfactory Receptor 5D16 3
  • OR11-154 3

External Ids for OR5D16 Gene

Previous GeneCards Identifiers for OR5D16 Gene

  • GC11U990431
  • GC11P055382
  • GC11P055365
  • GC11P055607

Summaries for OR5D16 Gene

Entrez Gene Summary for OR5D16 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5D16 Gene

OR5D16 (Olfactory Receptor, Family 5, Subfamily D, Member 16) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5D14.

UniProtKB/Swiss-Prot for OR5D16 Gene

  • Odorant receptor.

Gene Wiki entry for OR5D16 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5D16 Gene

Genomics for OR5D16 Gene

Regulatory Elements for OR5D16 Gene

Genomic Location for OR5D16 Gene

55,838,752 bp from pter
55,839,738 bp from pter
987 bases
Plus strand

Genomic View for OR5D16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5D16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5D16 Gene

Proteins for OR5D16 Gene

  • Protein details for OR5D16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 5D16
    Protein Accession:
    Secondary Accessions:
    • Q6IF65
    • Q96RB4

    Protein attributes for OR5D16 Gene

    328 amino acids
    Molecular mass:
    37278 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5D16 Gene

Proteomics data for OR5D16 Gene at MOPED

Post-translational modifications for OR5D16 Gene

  • Glycosylation at Asn7
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5D16 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for OR5D16

No data available for DME Specific Peptides for OR5D16 Gene

Domains for OR5D16 Gene

Gene Families for OR5D16 Gene

Protein Domains for OR5D16 Gene

Suggested Antigen Peptide Sequences for OR5D16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5D16: view

Function for OR5D16 Gene

Molecular function for OR5D16 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5D16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5D16: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR5D16

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5D16 Gene

Localization for OR5D16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5D16 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR5D16 Gene COMPARTMENTS Subcellular localization image for OR5D16 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5D16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR5D16: view

Pathways for OR5D16 Gene

genes like me logo Genes that share pathways with OR5D16: view

Pathways by source for OR5D16 Gene

Interacting Proteins for OR5D16 Gene

Gene Ontology (GO) - Biological Process for OR5D16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5D16: view

Transcripts for OR5D16 Gene

mRNA/cDNA for OR5D16 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR5D16

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR5D16 Gene

No ASD Table

Relevant External Links for OR5D16 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR5D16 Gene

mRNA expression in normal human tissues for OR5D16 Gene

SOURCE GeneReport for Unigene cluster for OR5D16 Gene Hs.554527

genes like me logo Genes that share expressions with OR5D16: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR5D16 Gene

Orthologs for OR5D16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5D16 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR5D18 35
  • 82.42 (n)
  • 78.14 (a)
-- 36
  • 62 (a)
(Canis familiaris)
Mammalia OR5D18 35
  • 83.92 (n)
  • 81.35 (a)
-- 36
  • 60 (a)
(Mus musculus)
Mammalia Olfr73 35
  • 77.49 (n)
  • 78.14 (a)
Olfr1155 16
Olfr1155 36
  • 81 (a)
(Rattus norvegicus)
Mammalia LOC686683 35
  • 78.67 (n)
  • 76.85 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 67 (a)
Species with no ortholog for OR5D16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5D16 Gene

Gene Tree for OR5D16 (if available)
Gene Tree for OR5D16 (if available)

Paralogs for OR5D16 Gene

Paralogs for OR5D16 Gene

(441) SIMAP similar genes for OR5D16 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5D16: view

Variants for OR5D16 Gene

Sequence variations from dbSNP and Humsavar for OR5D16 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs6591699 -- 55,838,826(+) GAACT(G/T)CAAAT reference, synonymous-codon
rs6591700 - 55,839,217(+) GAGTC(A/G)CATGT missense, reference
rs7105503 -- 55,838,380(+) AAATA(C/G)TTATT upstream-variant-2KB
rs10792360 -- 55,836,936(+) TCTAG(C/T)GGATG upstream-variant-2KB
rs10897297 -- 55,838,278(+) CTATA(A/T)CACAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5D16 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv821668 CNV Loss 15273396
esv782 CNV CNV 17122850
nsv428256 CNV Loss 18775914
nsv437717 CNV Loss 16327808
dgv382e1 CNV Complex 17122850
dgv50e55 CNV Loss 17911159
dgv383e1 CNV Complex 17122850
dgv51e55 CNV Loss 17911159
nsv469885 CNV Loss 16826518
nsv832158 CNV Gain 17160897

Relevant External Links for OR5D16 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5D16 Gene

Disorders for OR5D16 Gene

No disorders were found for OR5D16 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR5D16 Gene

Publications for OR5D16 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR5D16 Gene

Sources for OR5D16 Gene

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