Aliases for RND3 Gene
External Ids for RND3 Gene
Previous HGNC Symbols for RND3 Gene
Previous GeneCards Identifiers for RND3 Gene
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
GeneCards Summary for RND3 Gene
RND3 (Rho Family GTPase 3) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Development EGFR signaling pathway. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RHOA.
UniProtKB/Swiss-Prot for RND3 Gene
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.