Aliases for CXCL10 Gene
External Ids for CXCL10 Gene
Previous HGNC Symbols for CXCL10 Gene
Previous GeneCards Identifiers for CXCL10 Gene
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]
GeneCards Summary for CXCL10 Gene
CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. Diseases associated with CXCL10 include endotheliitis and severe acute respiratory syndrome. Among its related pathways are Signaling by GPCR and Complement and coagulation cascades. GO annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CXCL9.
UniProtKB/Swiss-Prot for CXCL10 Gene
Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.