Aliases for IMPG1 Gene
External Ids for IMPG1 Gene
Previous HGNC Symbols for IMPG1 Gene
Previous GeneCards Identifiers for IMPG1 Gene
This gene encodes a protein that is a major component of the retinal interphotoreceptor matrix. The encoded protein is a proteoglycan that is thought to play a role in maintaining viability of photoreceptor cells and in adhesion of the neural retina to the retinal pigment epithelium. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
GeneCards Summary for IMPG1 Gene
IMPG1 (Interphotoreceptor Matrix Proteoglycan 1) is a Protein Coding gene. Diseases associated with IMPG1 include Macular Dystrophy, Vitelliform, 4 and Macular Dystrophy, Vitelliform, 3. Among its related pathways are ERK Signaling and Phospholipase-C Pathway. GO annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is IMPG2.
UniProtKB/Swiss-Prot for IMPG1 Gene
May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix.