Aliases for IMPG1 Gene
External Ids for IMPG1 Gene
Previous HGNC Symbols for IMPG1 Gene
Previous GeneCards Identifiers for IMPG1 Gene
This gene encodes a protein that is a major component of the retinal interphotoreceptor matrix. The encoded protein is a proteoglycan that is thought to play a role in maintaining viability of photoreceptor cells and in adhesion of the neural retina to the retinal pigment epithelium. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
GeneCards Summary for IMPG1 Gene
IMPG1 (Interphotoreceptor Matrix Proteoglycan 1) is a Protein Coding gene. Diseases associated with IMPG1 include Macular Dystrophy, Vitelliform, 4 and Macular Dystrophy, Vitelliform, 3. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is IMPG2.
UniProtKB/Swiss-Prot for IMPG1 Gene
May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix.