Aliases for CXCR2 Gene
Aliases for CXCR2 Gene
External Ids for CXCR2 Gene
- HGNC: 6027
- Entrez Gene: 3579
- Ensembl: ENSG00000180871
- OMIM: 146928
- UniProtKB: P25025
Previous HGNC Symbols for CXCR2 Gene
- IL8RB
Previous GeneCards Identifiers for CXCR2 Gene
- GC02P218699
- GC02P218991
- GC02P210842
- GC02P218994
- GC02P219006
- GC02P219012
- GC02P219021
Summaries for CXCR2 Gene
-
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]
GeneCards Summary for CXCR2 Gene
CXCR2 (C-X-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CXCR2 include Autosomal Recessive Severe Congenital Neutropenia Due To Cxcr2 Deficiency and Neutrophil Migration. Among its related pathways are Akt Signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-X-C chemokine receptor activity. An important paralog of this gene is CXCR1.
UniProtKB/Swiss-Prot for CXCR2 Gene
-
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
-
Chemokine CXC receptors (CXCRs) predominantly recognize CXC chemokines. CXC chemokines are distinguished by having four conserved cysteines, with the first two cysteines being separated by a single amino acid. There are six chemokine CXC receptors.
Additional gene information for CXCR2 Gene
- Monarch Initiative
- Search for CXCR2 at DataMed
- Search for CXCR2 at HumanCyc
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXCR2 Gene
Genomics for CXCR2 Gene
GeneHancer (GH) Regulatory Elements for CXCR2 Gene
Promoters and enhancers for CXCR2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CXCR2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CXCR2 Gene
Genomic Locations for CXCR2 Gene
- chr2:218,125,289-218,137,253
- (GRCh38/hg38)
- Size:
- 11,965 bases
- Orientation:
- Plus strand
- chr2:218,990,012-219,001,976
- (GRCh37/hg19)
Genomic View for CXCR2 Gene
Genes around CXCR2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q35 by Ensembl
- 2q35 by Entrez Gene
- 2q35 by HGNC
CXCR2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CXCR2 Gene
Proteins for CXCR2 Gene
-
Protein details for CXCR2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P25025-CXCR2_HUMAN
- Recommended name:
- C-X-C chemokine receptor type 2
- Protein Accession:
- P25025
- Q8IUZ1
- Q9P2T6
- Q9P2T7
Protein attributes for CXCR2 Gene
- Size:
- 360 amino acids
- Molecular mass:
- 40759 Da
- Quaternary structure:
- No Data Available
Protein Expression for CXCR2 Gene
Post-translational modifications for CXCR2 Gene
- Phosphorylated upon ligand binding; which is required for desensitization.
- Glycosylation at Asn22
Other Protein References for CXCR2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CXCR2 (CXCR2/IL-8 RB)
-
Custom Antibody ServicesOriGene Antibodies for CXCR2
- Novus Biologicals Antibodies for CXCR2
-
Abcam antibodies for CXCR2
-
Cloud-Clone Corp. Antibodies for CXCR2
- Invitrogen Antibodies for CXCR2
- antibodies-online: Search results for 286 available CXCR2 Antibodies ranked by validation data
- Compare Top CXCR2 Antibodies
-
Recommended
- 65 WB Antibodies (anti-human)
- 56 IHC (p) Antibodies (anti-human)
- 46 FACS Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 4 IP Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 17 FACS Antibodies (anti-rat)
- 1 IF Antibody (anti-mouse)
- 5 IHC (p) Antibodies (anti-mouse)
- 6 Neut Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 27 WB Antibodies (anti-mouse)
- 35 FACS Antibodies (anti-mouse)
- 2 ICFC Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 5 Neut Antibodies (anti-human)
- 6 IP Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 46 FACS Antibodies (anti-human)
- 56 IHC (p) Antibodies (anti-human)
- 65 WB Antibodies (anti-human)
- 4 IP Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 17 FACS Antibodies (anti-rat)
- 1 IF Antibody (anti-mouse)
- 5 IHC (p) Antibodies (anti-mouse)
- 6 Neut Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 27 WB Antibodies (anti-mouse)
- 35 FACS Antibodies (anti-mouse)
- 2 ICFC Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 5 Neut Antibodies (anti-human)
- 6 IP Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 46 FACS Antibodies (anti-human)
- 56 IHC (p) Antibodies (anti-human)
- 65 WB Antibodies (anti-human)
- 4 IP Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 17 FACS Antibodies (anti-rat)
- 1 IF Antibody (anti-mouse)
- 5 IHC (p) Antibodies (anti-mouse)
- 6 Neut Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 27 WB Antibodies (anti-mouse)
- 35 FACS Antibodies (anti-mouse)
- 2 ICFC Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 5 Neut Antibodies (anti-human)
- 6 IP Antibodies (anti-human)
- GeneTex CXCR2 antibody for CXCR2
-
Custom Antibody ServicesProSci Antibodies for CXCR2
-
Santa Cruz Biotechnology (SCBT) Antibodies for CXCR2
Protein Products
-
OriGene Purified Proteins for CXCR2
- Search Origene for MassSpec and Protein Over-expression Lysates for CXCR2
- Origene Custom Protein Services for CXCR2
-
Cloud-Clone Corp. Proteins for CXCR2
- Search GeneTex for Proteins for CXCR2
-
Abcam proteins for CXCR2
Assay Products
-
Cloud-Clone Corp. Assay Kits for CXCR2
- antibodies-online: Search results for 43 available CXCR2 Elisa Kits ranked by validation data
- Compare Top CXCR2 Elisa Kits
-
Recommended
- 1 Chicken ELISA Kit
- 3 Cow (Bovine) ELISA Kits
- 2 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 1 Guinea Pig ELISA Kit
- 12 Human ELISA Kits
- 1 Monkey ELISA Kit
- 10 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 1 Rabbit ELISA Kit
- 9 Rat (Rattus) ELISA Kits
- 1 Sheep (Ovine) ELISA Kit
- 1 Chicken ELISA Kit
- 3 Cow (Bovine) ELISA Kits
- 2 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 1 Guinea Pig ELISA Kit
- 12 Human ELISA Kits
- 1 Monkey ELISA Kit
- 10 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 1 Rabbit ELISA Kit
- 9 Rat (Rattus) ELISA Kits
- 1 Sheep (Ovine) ELISA Kit
- 1 Chicken ELISA Kit
- 3 Cow (Bovine) ELISA Kits
- 2 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 1 Guinea Pig ELISA Kit
- 12 Human ELISA Kits
- 1 Monkey ELISA Kit
- 10 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 1 Rabbit ELISA Kit
- 9 Rat (Rattus) ELISA Kits
- 1 Sheep (Ovine) ELISA Kit
No data available for DME Specific Peptides for CXCR2 Gene
Domains & Families for CXCR2 Gene
Gene Families for CXCR2 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- CD markers
- G-protein coupled receptors
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for CXCR2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CXCR2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P25025- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for CXCR2 Gene
Molecular function for CXCR2 Gene
- UniProtKB/Swiss-Prot Function:
- Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Phenotypes From GWAS Catalog for CXCR2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004871 | signal transducer activity | IDA,IEA | 10438939 |
| GO:0004918 | interleukin-8 receptor activity | IDA | 10820279 |
| GO:0004930 | G-protein coupled receptor activity | IEA | -- |
| GO:0004950 | chemokine receptor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 22904195 |
Phenotypes for CXCR2 Gene
- MGI mutant phenotypes for CXCR2:
-
inferred from 4 alleles
- nervous system phenotype
- homeostasis/metabolism phenotype
- respiratory system phenotype
- cardiovascular system phenotype
- mortality/aging
- immune system phenotype
- cellular phenotype
- growth/size/body region phenotype
- neoplasm
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- vision/eye phenotype
- hematopoietic system phenotype
- skeleton phenotype
- renal/urinary system phenotype
- liver/biliary system phenotype
- GenomeRNAi human phenotypes for CXCR2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXCR2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CXCR2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXCR2 gene
- Search ViGene Biosciences for CXCR2
CRISPR Products
-
OriGene CRISPR knockouts for CXCR2
- genomics-online: gRNA clones - Search results for 150 available CXCR1 gene related products
- Overview of 150 available CXCR1 gene related products
-
Recommended
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- Applied Biological Materials CRISPR for CXCR2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXCR2
- GenScript: Design CRISPR guide RNA sequences for CXCR2
miRNA for CXCR2 Gene
- miRTarBase miRNAs that target CXCR2
-
- hsa-mir-335-5p (MIRT017358)
- bta-mir-145 (MIRT053906)
- hsa-mir-5096 (MIRT647720)
- hsa-mir-3187-3p (MIRT647721)
- hsa-mir-4435 (MIRT647722)
- hsa-mir-588 (MIRT647723)
- hsa-mir-4701-5p (MIRT647724)
- hsa-mir-548s (MIRT647725)
- hsa-mir-6802-3p (MIRT647726)
- hsa-mir-411-5p (MIRT647727)
- hsa-mir-6832-5p (MIRT647728)
- hsa-mir-3194-5p (MIRT647729)
- hsa-mir-29a-5p (MIRT647730)
- hsa-mir-1306-3p (MIRT647731)
- hsa-mir-6849-3p (MIRT647732)
- hsa-mir-6823-5p (MIRT647733)
- hsa-mir-4293 (MIRT647734)
- hsa-mir-4524b-3p (MIRT647735)
- hsa-mir-22-3p (MIRT732336)
miRNA Products
- Search ViGene Biosciences for CXCR2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CXCR2
- Browse OriGene Inhibitory RNA Products For CXCR2
- genomics-online: shRNA clones - Search results for 150 available CXCR1 gene related products
- Overview of 150 available CXCR1 gene related products
-
Recommended
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
-
ViGene Biosciences ready-to-package AAV shRNAs for CXCR2 gene
Clone Products
- Sino Biological Human cDNA Clone for CXCR2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CXCR2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXCR2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CXCR2
- genomics-online: cdna clones - Search results for 150 available CXCR2 gene related products
- Overview of 150 available CXCR2 gene related products
-
Recommended
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- orf clones - Search results for 150 available CXCR1 gene related products
- Overview of 150 available CXCR1 gene related products
-
Recommended
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- Applied Biological Materials Clones for CXCR2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CXCR2 (CXCR2/IL-8 RB)
Cell Line Products
-
Horizon Cell Lines for CXCR2
-
ViGene Biosciences adenoviral particle packaged cDNA for CXCR2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CXCR2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXCR2 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CXCR2 Gene
Localization for CXCR2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CXCR2 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| lysosome | 5 |
| extracellular | 2 |
| cytoskeleton | 2 |
| nucleus | 1 |
| cytosol | 1 |
| endosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IDA | 10878382 |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 10438939 |
| GO:0009986 | cell surface | IDA | 10878382 |
| GO:0016020 | membrane | IEA,IDA | 10725748 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CXCR2 Gene
Pathways & Interactions for CXCR2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors |
.34
|
|
| 2 | Akt Signaling |
.60
.60
|
|
| 3 | Signaling by GPCR | ||
| 4 | Innate Immune System |
.61
|
|
| 5 | CCR5 Pathway in Macrophages | ||
Pathways by source for CXCR2 Gene
3 BioSystems pathways for CXCR2 Gene
11 Reactome pathways for CXCR2 Gene
1 GeneGo (Thomson Reuters) pathway for CXCR2 Gene
1 R&D Systems pathway for CXCR2 Gene
8 Qiagen pathways for CXCR2 Gene
Interacting Proteins for CXCR2 Gene
Selected Interacting proteins:
ENSP00000319635
P25025-CXCR2_HUMAN
for CXCR2 Gene via
STRING
MINT
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002407 | dendritic cell chemotaxis | TAS | 16621978 |
| GO:0002438 | acute inflammatory response to antigenic stimulus | IEA | -- |
| GO:0002690 | positive regulation of leukocyte chemotaxis | IEA | -- |
| GO:0006935 | chemotaxis | IDA,IEA | 10725748 |
| GO:0006954 | inflammatory response | TAS | 9725262 |
Drugs & Compounds for CXCR2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Fludarabine | Approved | Pharma | DNA synthsis inhibitor | 1231,1231 | ||
| calcium | Approved | Nutra | 0 | |||
| Aldesleukin | Approved | Pharma | 419 | |||
| Cyclophosphamide | Approved, Investigational | Pharma | Nitrogen mustard alkylating agent and prodrug. | 3113 | ||
| Mesna | Approved, Investigational | Pharma | 275 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| [<sup>125</sup>I]CXCL1 |
|
Full agonist, Agonist |
|
|
||
| [<sup>125</sup>I]CXCL5 |
|
Full agonist, Agonist |
|
|
||
| [<sup>125</sup>I]CXCL7 |
|
Full agonist, Agonist |
|
|
(5) Tocris Compounds for CXCR2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| AF 12198 | Potent, selective human type I IL-1 receptor antagonist | 185413-30-3 |
| Lyn peptide inhibitor | Inhibits Lyn-dependent activities of IL-5 receptor; cell-permeable | 222018-18-0 |
| R 7050 | Inhibitor of TNF-alpha receptor 1 signaling | 303997-35-5 |
| Ro 26-4550 trifluoroacetate | Competitive inhibitor of IL-2/ IL-2Ralpha receptor interaction | 1217448-66-2 |
| YM 90709 | Interleukin-5 receptor antagonist | 163769-88-8 |
(9) ApexBio Compounds for CXCR2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Plerixafor 8HCl (AMD3100 8HCl) | CXCR4 antagonist | 155148-31-5 |
| Reparixin | Inhibitor of CXCL8 receptor and CXCR1/CXCR2 activation | 266359-83-5 |
| Reparixin L-lysine salt | CXCR1/CXCR2 inhibitor | 266359-93-7 |
| SB 225002 | CXCR2 antagonist, potent and selective | 182498-32-4 |
| SB 265610 | CXCR2 antagonist, potent | 211096-49-0 |
| SCH 527123 | CXCR1 and CXCR2 receptors antagonist | 473727-83-2 |
| SCH 563705 | CXCR2/CXCR1 antagonist,potent | 473728-58-4 |
| SRT3190 | CXCR2 ligand,SIRT1 activator | 1204707-73-2 |
| WZ811 | Competitive CXR4 antagonist,highly potent | 55778-02-4 |
Transcripts for CXCR2 Gene
mRNA/cDNA for CXCR2 Gene
- (6) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (25) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CXCR2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CXCR2
- genomics-online: gRNA clones - Search results for 150 available CXCR1 gene related products
- Overview of 150 available CXCR1 gene related products
-
Recommended
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- Applied Biological Materials CRISPR for CXCR2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXCR2
- GenScript: Design CRISPR guide RNA sequences for CXCR2
miRNA Products
- Search ViGene Biosciences for CXCR2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CXCR2
- Browse OriGene Inhibitory RNA Products For CXCR2
- genomics-online: shRNA clones - Search results for 150 available CXCR1 gene related products
- Overview of 150 available CXCR1 gene related products
-
Recommended
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
-
ViGene Biosciences ready-to-package AAV shRNAs for CXCR2 gene
Clone Products
- Sino Biological Human cDNA Clone for CXCR2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CXCR2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXCR2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CXCR2
- genomics-online: cdna clones - Search results for 150 available CXCR2 gene related products
- Overview of 150 available CXCR2 gene related products
-
Recommended
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- orf clones - Search results for 150 available CXCR1 gene related products
- Overview of 150 available CXCR1 gene related products
-
Recommended
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- Applied Biological Materials Clones for CXCR2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CXCR2 (CXCR2/IL-8 RB)
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: |
Expression for CXCR2 Gene
mRNA differential expression in normal tissues according to GTEx for CXCR2 Gene
This gene is overexpressed in Whole Blood (x48.3).
This gene is overexpressed in Nasal epithelium (66.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CXCR2 Gene
NURSA nuclear receptor signaling pathways regulating expression of CXCR2 Gene:
CXCR2SOURCE GeneReport for Unigene cluster for CXCR2 Gene:
Hs.846Evidence on tissue expression from TISSUES for CXCR2 Gene
- Blood(4.8)
- Nervous system(4.3)
- Lung(2.7)
- Intestine(2.6)
- Spleen(2.4)
- Bone marrow(2.3)
- Heart(2)
- Skin(2)
Primer Products
-
OriGene qPCR primer pairs for CXCR2
-
OriGene qPCR primer pairs and template standards for CXCR2
- genomics-online: primer clones - Search results for 150 available CXCR1 gene related products
- Overview of 150 available CXCR1 gene related products
-
Recommended
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
- pGEM-T
- pCMV3-C-OFPSpark
- pCMV3-C-GFPSpark
- pCMV3-SP-N-Myc
- pCMV3-SP-N-His
- pCMV3-SP-N-HA
- pCMV3-SP-N-FLAG
- pCMV3-C-Myc
- pCMV3-C-His
- pCMV3-C-HA
- pCMV3-C-FLAG
- pcDNA3.1+C-(K)-DYK
- pGFP-V-RS
- pCMV6-Entry
- pCMV6-AC
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CXCR2 Gene
Orthologs for CXCR2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CXCR2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | CXCR2 33 34 |
|
||
| -- 34 |
|
OneToMany | |||
| cow (Bos Taurus) |
Mammalia | CXCR2 33 34 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Cxcr2 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cxcr2 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC101732165 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC796724 33 |
|
||
| CXCR1 34 |
|
OneToMany |
- Species where no ortholog for CXCR2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CXCR2 Gene
Paralogs for CXCR2 Gene
(65) SIMAP similar genes for CXCR2 Gene using alignment to 5 proteins:
- IL8RB
- CXCR1
- CCR2
- CCR7
- CCR6
- C3AR1
- CX3CR1
- CCR4
- ACKR2
- CCR5
- CCBP2
- CCR8
- CCR-5
- FPR2
- AGTR1
- CMKLR1
- XCR1
- HCRTR2
- CCR9
- CCR3
- SSTR5
- BDKRB1
- CXCR6
- CXCR4
- BLR1
- CXCR5
- FPR1
- CXCR3
- CCR1
- AGTR2
- OPRM1
- LPAR6
- GPR85
- CCRL1
- ADRA1A
- ACKR4
- ACKR3
- SSTR4
- SSTR1
- LPAR5
- KPG_010
- P2RY6
- GPR15
- FPRL2
- FPR3
- OPRK1
- DKFZp686O088
- CCR10
- BDKRB2
- GPR1
- SSTR2
- OXGR1
- QRFPR
- CYSLTR1
- gpcr
- LPAR4
- gamrh
- OPRL1
- GALR1
- C5AR1
- NPBWR2
- GPR25
- KPG_011
- CYSLTR2
- APLNR
Pseudogenes.org Pseudogenes for CXCR2 Gene
Variants for CXCR2 Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs149364972 | likely-benign, not specified | 218,135,036(+) | G/A/T | coding_sequence_variant, missense_variant | |
| rs1000203679 | -- | 218,134,137(+) | T/C | intron_variant | |
| rs1000470944 | -- | 218,125,923(+) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000720972 | -- | 218,134,456(+) | T/C | intron_variant | |
| rs1000821382 | -- | 218,133,443(+) | G/C | intron_variant |
Residual Variation Intolerance Score:
32.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.50;
29.18% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CXCR2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXCR2 Gene
Disorders for CXCR2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| autosomal recessive severe congenital neutropenia due to cxcr2 deficiency |
|
|
| neutrophil migration |
|
|
| human granulocytic anaplasmosis |
|
|
| acute pyelonephritis |
|
|
| septicemic plague |
|
|
Search CXCR2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CXCR2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CXCR2 Gene
Publications for CXCR2 Gene
- Single nucleotide polymorphisms in the coding regions of human CXC-chemokine receptors CXCR1, CXCR2 and CXCR3. (PMID: 11196695) Kato H … Tokunaga K (Genes and immunity 2000) 3 4 22 58
- Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor. (PMID: 9079638) Mueller SG … Richmond A (The Journal of biological chemistry 1997) 3 4 22 58
- Comparison of the genomic organization and promoter function for human interleukin-8 receptors A and B. (PMID: 7929358) Ahuja SK … Murphy PM (The Journal of biological chemistry 1994) 3 4 22 58
- Characterization of two high affinity human interleukin-8 receptors. (PMID: 1379593) Lee J … Wood WI (The Journal of biological chemistry 1992) 3 4 22 58
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. (PMID: 21297633) Anderson CA … Rioux JD (Nature genetics 2011) 3 44 58
Products for CXCR2 Gene
- R&D Systems Antibodies for CXCR2 (CXCR2/IL-8 RB)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- R&D Systems cDNA Clones for CXCR2 (CXCR2/IL-8 RB)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CXCR2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CXCR2
- Search Origene for MassSpec and Protein Over-expression Lysates for CXCR2
- Origene Custom Protein Services for CXCR2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CXCR2
- Browse OriGene Inhibitory RNA Products For CXCR2
- OriGene qPCR primer pairs and template standards for CXCR2
- OriGene qPCR primer pairs for CXCR2
- OriGene CRISPR knockouts for CXCR2
- OriGene ORF clones in human for CXCR2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CXCR2
- GenScript: Next-day shipping of latest version cDNA ORF clones for CXCR2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CXCR2
- GenScript Custom Assay Services for CXCR2
- GenScript Custom overexpressing Cell Line Services for CXCR2
- GenScript: Design CRISPR guide RNA sequences for CXCR2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CXCR2
- Sino Biological Human cDNA Clone for CXCR2
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CXCR2
- Novus Biologicals proteins and lysates for CXCR2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for CXCR2
- Abcam proteins for CXCR2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Cloud-Clone Corp. Antibodies for CXCR2
- Cloud-Clone Corp. Proteins for CXCR2
- Cloud-Clone Corp. Assay Kits for CXCR2
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for CXCR2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for CXCR2
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXCR2
- VectorBuilder custom plasmid, inducible vectors for CXCR2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXCR2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CXCR2
- antibodies-online: Search results for 286 available CXCR2 Antibodies ranked by validation data
- Compare Top CXCR2 Antibodies
- Recommended
- 65 WB Antibodies (anti-human)
- 56 IHC (p) Antibodies (anti-human)
- 46 FACS Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 6 IP Antibodies (anti-human)
- 5 Neut Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 2 ICFC Antibodies (anti-human)
- 35 FACS Antibodies (anti-mouse)
- 27 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 6 Neut Antibodies (anti-mouse)
- 5 IHC (p) Antibodies (anti-mouse)
- 1 IF Antibody (anti-mouse)
- 17 FACS Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 4 IP Antibodies (anti-rat)
- 65 WB Antibodies (anti-human)
- 56 IHC (p) Antibodies (anti-human)
- 46 FACS Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 6 IP Antibodies (anti-human)
- 5 Neut Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 2 ICFC Antibodies (anti-human)
- 35 FACS Antibodies (anti-mouse)
- 27 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 6 Neut Antibodies (anti-mouse)
- 5 IHC (p) Antibodies (anti-mouse)
- 1 IF Antibody (anti-mouse)
- 17 FACS Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 4 IP Antibodies (anti-rat)
- 65 WB Antibodies (anti-human)
- 56 IHC (p) Antibodies (anti-human)
- 46 FACS Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 6 IP Antibodies (anti-human)
- 5 Neut Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 2 ICFC Antibodies (anti-human)
- 35 FACS Antibodies (anti-mouse)
- 27 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 6 Neut Antibodies (anti-mouse)
- 5 IHC (p) Antibodies (anti-mouse)
- 1 IF Antibody (anti-mouse)
- 17 FACS Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 4 IP Antibodies (anti-rat)
- antibodies-online: Search results for 43 available CXCR2 Elisa Kits ranked by validation data
- Compare Top CXCR2 Elisa Kits
- Recommended
- 1 Chicken ELISA Kit
- 3 Cow (Bovine) ELISA Kits
- 2 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 1 Guinea Pig ELISA Kit
- 12 Human ELISA Kits
- 1 Monkey ELISA Kit
- 10 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 1 Rabbit ELISA Kit
- 9 Rat (Rattus) ELISA Kits
- 1 Sheep (Ovine) ELISA Kit
- 1 Chicken ELISA Kit
- 3 Cow (Bovine) ELISA Kits
- 2 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 1 Guinea Pig ELISA Kit
- 12 Human ELISA Kits
- 1 Monkey ELISA Kit
- 10 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 1 Rabbit ELISA Kit
- 9 Rat (Rattus) ELISA Kits
- 1 Sheep (Ovine) ELISA Kit
- 1 Chicken ELISA Kit
- 3 Cow (Bovine) ELISA Kits
- 2 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 1 Guinea Pig ELISA Kit
- 12 Human ELISA Kits
- 1 Monkey ELISA Kit
- 10 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 1 Rabbit ELISA Kit
- 9 Rat (Rattus) ELISA Kits
- 1 Sheep (Ovine) ELISA Kit
- antibodies-online: Search results for 8 available CXCR2 Proteins ranked by validation data
- Compare Top CXCR2 Proteins
- GeneTex CXCR2 antibody for CXCR2
- Search GeneTex for Proteins for CXCR2
- ViGene Biosciences adenoviral particle packaged cDNA for CXCR2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CXCR2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CXCR2 gene
- Search ViGene Biosciences for CXCR2
- Santa Cruz Biotechnology (SCBT) Antibodies for CXCR2
- Search Santa Cruz Biotechnology (SCBT) for CXCR2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CXCR2
- Horizon Cell Lines for CXCR2
- genomics-online: cdna clones - Search results for 150 available CXCR2 gene related products
- Overview of 150 available CXCR2 gene related products
- Recommended
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- orf clones - Search results for 150 available CXCR2 gene related products
- Overview of 150 available CXCR2 gene related products
- Recommended
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- genomics-online: gRNA clones - Search results for 150 available CXCR2 gene related products
- Overview of 150 available CXCR2 gene related products
- Recommended
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- genomics-online: primer clones - Search results for 150 available CXCR2 gene related products
- Overview of 150 available CXCR2 gene related products
- Recommended
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- genomics-online: shRNA clones - Search results for 150 available CXCR2 gene related products
- Overview of 150 available CXCR2 gene related products
- Recommended
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
- pCMV6-AC
- pCMV6-Entry
- pGFP-V-RS
- pcDNA3.1+C-(K)-DYK
- pCMV3-C-FLAG
- pCMV3-C-HA
- pCMV3-C-His
- pCMV3-C-Myc
- pCMV3-SP-N-FLAG
- pCMV3-SP-N-HA
- pCMV3-SP-N-His
- pCMV3-SP-N-Myc
- pCMV3-C-GFPSpark
- pCMV3-C-OFPSpark
- pGEM-T
Sources for CXCR2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71)