Aliases for IL2RG Gene
External Ids for IL2RG Gene
Previous Symbols for IL2RG Gene
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]
GeneCards Summary for IL2RG Gene
IL2RG (Interleukin 2 Receptor, Gamma) is a Protein Coding gene. Diseases associated with IL2RG include severe combined immunodeficiency, x-linked and combined immunodeficiency, x-linked, moderate. Among its related pathways are PI3K-Akt signaling pathway and Akt Signaling. GO annotations related to this gene include interleukin-2 receptor activity and interleukin-4 receptor activity.
UniProtKB/Swiss-Prot for IL2RG Gene
Common subunit for the receptors for a variety of interleukins