External Ids for APOD Gene
Previous GeneCards Identifiers for APOD Gene
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
GeneCards Summary for APOD Gene
APOD (Apolipoprotein D) is a Protein Coding gene. Diseases associated with APOD include Breast Cyst and Niemann-Pick Disease. Among its related pathways are Transport of vitamins, nucleosides, and related molecules and Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF). Gene Ontology (GO) annotations related to this gene include transporter activity and cholesterol binding.
UniProtKB/Swiss-Prot for APOD Gene
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.