Aliases for IDS Gene
External Ids for IDS Gene
Previous Symbols for IDS Gene
The protein encoded by this gene belongs to the sulfatase family, is localized to the lysosome, and is involved in lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease, mucopolysaccharidosis type II, also known as Hunter syndrome. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2013]
GeneCards Summary for IDS Gene
IDS (Iduronate 2-Sulfatase) is a Protein Coding gene. Diseases associated with IDS include tolosa-hunt syndrome and mucopolysaccharidosis ii. Among its related pathways are Disease and Lysosome. GO annotations related to this gene include iduronate-2-sulfatase activity. An important paralog of this gene is ARSK.
UniProtKB/Swiss-Prot for IDS Gene
Required for the lysosomal degradation of heparan sulfate and dermatan sulfate