Aliases for HSPA2 Gene
External Ids for HSPA2 Gene
Previous GeneCards Identifiers for HSPA2 Gene
GeneCards Summary for HSPA2 Gene
HSPA2 (Heat Shock 70kDa Protein 2) is a Protein Coding gene. Diseases associated with HSPA2 include varicocele. Among its related pathways are MAPK signaling pathway and Cell Cycle, Mitotic. GO annotations related to this gene include enzyme binding and glycolipid binding. An important paralog of this gene is HSPA14.
UniProtKB/Swiss-Prot for HSPA2 Gene
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage