Aliases for HOXB7 Gene
External Ids for HOXB7 Gene
Previous HGNC Symbols for HOXB7 Gene
Previous GeneCards Identifiers for HOXB7 Gene
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXB7 Gene
HOXB7 (Homeobox B7) is a Protein Coding gene. Diseases associated with HOXB7 include ovarian endodermal sinus tumor and ovarian primitive germ cell tumor. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is HOXA7.
UniProtKB/Swiss-Prot for HOXB7 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.