Aliases for HOXB3 Gene
External Ids for HOXB3 Gene
Previous Symbols for HOXB3 Gene
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXB3 Gene
HOXB3 (Homeobox B3) is a Protein Coding gene. Diseases associated with HOXB3 include myeloid leukemia and vacterl association. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and RNA polymerase II core promoter sequence-specific DNA binding. An important paralog of this gene is EVX1.
UniProtKB/Swiss-Prot for HOXB3 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis