Aliases for HPCA Gene
External Ids for HPCA Gene
Previous GeneCards Identifiers for HPCA Gene
The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species. [provided by RefSeq, Jul 2008]
GeneCards Summary for HPCA Gene
HPCA (Hippocalcin) is a Protein Coding gene. Diseases associated with HPCA include Dystonia 2, Torsion, Autosomal Recessive and Dystonia 2. GO annotations related to this gene include calcium ion binding and actin binding. An important paralog of this gene is HPCAL1.
UniProtKB/Swiss-Prot for HPCA Gene
Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels (PubMed:28398555). May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases (By similarity).