Aliases for HLX Gene
External Ids for HLX Gene
Previous HGNC Symbols for HLX Gene
Previous GeneCards Identifiers for HLX Gene
GeneCards Summary for HLX Gene
HLX (H2.0-Like Homeobox) is a Protein Coding gene. Diseases associated with HLX include congenital diaphragmatic hernia. Among its related pathways are IL12-mediated signaling events. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription regulatory region sequence-specific DNA binding. An important paralog of this gene is DBX2.
UniProtKB/Swiss-Prot for HLX Gene
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).