Aliases for GTF2E1 Gene
External Ids for GTF2E1 Gene
Previous GeneCards Identifiers for GTF2E1 Gene
GeneCards Summary for GTF2E1 Gene
GTF2E1 (General Transcription Factor IIE Subunit 1) is a Protein Coding gene. Diseases associated with GTF2E1 include Trichothiodystrophy 1, Photosensitive. Among its related pathways are RNA Polymerase II Transcription Initiation And Promoter Clearance and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding.
UniProtKB/Swiss-Prot for GTF2E1 Gene
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.