Aliases for P2RY8 Gene
External Ids for P2RY8 Gene
Previous GeneCards Identifiers for P2RY8 Gene
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008]
GeneCards Summary for P2RY8 Gene
P2RY8 (Purinergic Receptor P2Y, G-Protein Coupled, 8) is a Protein Coding gene. Diseases associated with P2RY8 include precursor b-cell acute lymphoblastic leukemia. Among its related pathways are Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and G-protein coupled purinergic nucleotide receptor activity. An important paralog of this gene is GPR132.
UniProtKB/Swiss-Prot for P2RY8 Gene
Probable receptor for purines coupled to G-proteins
P2Y receptors are G-protein-coupled receptors that respond to extracellular purine and pyrimidine nucleotides. To date, eight mammalian P2Y receptors are known (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11-14) as well as the non-mammalian p2y3, p2y8 and p2y receptors.