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Aliases for OR13C9 Gene

Aliases for OR13C9 Gene

  • Olfactory Receptor, Family 13, Subfamily C, Member 9 2 3
  • Olfactory Receptor OR9-13 3 4
  • OR9-13 3
  • OR37L 3

External Ids for OR13C9 Gene

Previous GeneCards Identifiers for OR13C9 Gene

  • GC09U990180
  • GC09M102760
  • GC09M104459
  • GC09M106419
  • GC09M107379

Summaries for OR13C9 Gene

Entrez Gene Summary for OR13C9 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13C9 Gene

OR13C9 (Olfactory Receptor, Family 13, Subfamily C, Member 9) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR13C7.

UniProtKB/Swiss-Prot for OR13C9 Gene

  • Odorant receptor.

Gene Wiki entry for OR13C9 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13C9 Gene

Genomics for OR13C9 Gene

Regulatory Elements for OR13C9 Gene

Genomic Location for OR13C9 Gene

Chromosome:
9
Start:
104,617,248 bp from pter
End:
104,618,204 bp from pter
Size:
957 bases
Orientation:
Minus strand

Genomic View for OR13C9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR13C9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13C9 Gene

Proteins for OR13C9 Gene

  • Protein details for OR13C9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGT0-O13C9_HUMAN
    Recommended name:
    Olfactory receptor 13C9
    Protein Accession:
    Q8NGT0
    Secondary Accessions:
    • Q6IFL2

    Protein attributes for OR13C9 Gene

    Size:
    318 amino acids
    Molecular mass:
    35854 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13C9 Gene

Proteomics data for OR13C9 Gene at MOPED

Post-translational modifications for OR13C9 Gene

Other Protein References for OR13C9 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

No data available for DME Specific Peptides for OR13C9 Gene

Domains & Families for OR13C9 Gene

Gene Families for OR13C9 Gene

Protein Domains for OR13C9 Gene

Suggested Antigen Peptide Sequences for OR13C9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGT0

UniProtKB/Swiss-Prot:

O13C9_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13C9: view

Function for OR13C9 Gene

Molecular function for OR13C9 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13C9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR13C9: view

Phenotypes for OR13C9 Gene

GenomeRNAi human phenotypes for OR13C9:
genes like me logo Genes that share phenotypes with OR13C9: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR13C9

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13C9 Gene

Localization for OR13C9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13C9 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR13C9 Gene COMPARTMENTS Subcellular localization image for OR13C9 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13C9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13C9: view

Pathways & Interactions for OR13C9 Gene

genes like me logo Genes that share pathways with OR13C9: view

Pathways by source for OR13C9 Gene

Interacting Proteins for OR13C9 Gene

Gene Ontology (GO) - Biological Process for OR13C9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13C9: view

No data available for SIGNOR curated interactions for OR13C9 Gene

Drugs & Compounds for OR13C9 Gene

No Compound Related Data Available

Transcripts for OR13C9 Gene

mRNA/cDNA for OR13C9 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR13C9

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13C9 Gene

No ASD Table

Relevant External Links for OR13C9 Gene

GeneLoc Exon Structure for
OR13C9
ECgene alternative splicing isoforms for
OR13C9

Expression for OR13C9 Gene

mRNA expression in normal human tissues for OR13C9 Gene

mRNA differential expression in normal tissues according to GTEx for OR13C9 Gene

This gene is overexpressed in Pituitary (x15.2), Brain - Cortex (x5.9), Cervix - Endocervix (x5.6), and Brain - Spinal cord (cervical c-1) (x4.5).

SOURCE GeneReport for Unigene cluster for OR13C9 Gene Hs.553682

genes like me logo Genes that share expression patterns with OR13C9: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR13C9 Gene

Orthologs for OR13C9 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR13C9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 86 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 89 (a)
ManyToMany
-- 36
  • 93 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
ManyToMany
-- 36
  • 84 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr159 36
  • 68 (a)
ManyToMany
Species with no ortholog for OR13C9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13C9 Gene

ENSEMBL:
Gene Tree for OR13C9 (if available)
TreeFam:
Gene Tree for OR13C9 (if available)

Paralogs for OR13C9 Gene

(451) SIMAP similar genes for OR13C9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR13C9: view

Variants for OR13C9 Gene

Sequence variations from dbSNP and Humsavar for OR13C9 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs993658 - 104,617,934(+) AATGG(A/T)CTTTC reference, missense
rs1425570 -- 104,620,129(+) ATTGG(A/G)AATGG upstream-variant-2KB
rs1425571 -- 104,620,149(+) CTTAA(A/C)CTTGC upstream-variant-2KB
rs1813819 -- 104,617,896(+) AAGCC(A/G)AGGAA synonymous-codon, reference
rs1834410 -- 104,616,861(+) AACAG(A/T)GGGCT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR13C9 Gene

Variant ID Type Subtype PubMed ID
nsv831677 CNV Gain 17160897
nsv893671 CNV Gain 21882294
nsv471313 CNV Loss 18288195
dgv2406e1 CNV Complex 17122850

Variation tolerance for OR13C9 Gene

Residual Variation Intolerance Score: 95.36% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 20.79; 99.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR13C9 Gene

HapMap Linkage Disequilibrium report
OR13C9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13C9 Gene

Disorders for OR13C9 Gene

Relevant External Links for OR13C9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR13C9
genes like me logo Genes that share disorders with OR13C9: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13C9 Gene

Publications for OR13C9 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 67
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 67
  3. Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. (PMID: 12906860) Hoppe R. … Strotmann J. (Genomics 2003) 67

Products for OR13C9 Gene

Sources for OR13C9 Gene

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