Aliases for DLL1 Gene
External Ids for DLL1 Gene
Previous GeneCards Identifiers for DLL1 Gene
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]
GeneCards Summary for DLL1 Gene
DLL1 (Delta-Like 1 (Drosophila)) is a Protein Coding gene. Diseases associated with DLL1 include chorea gravidarum and giant hemangioma. Among its related pathways are Signaling by GPCR and Downstream signaling events of B Cell Receptor (BCR). GO annotations related to this gene include calcium ion binding and Notch binding. An important paralog of this gene is NOTCH2.
UniProtKB/Swiss-Prot for DLL1 Gene
Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.