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Aliases for ZNF330 Gene

Aliases for ZNF330 Gene

  • Zinc Finger Protein 330 2 3
  • NOA36 3 4 6
  • Nucleolar Cysteine-Rich Protein 3 4
  • Nucleolar Autoantigen 36 3 4
  • Zinc Finger Autoantigen 330 3
  • HSA6591 3

External Ids for ZNF330 Gene

Previous GeneCards Identifiers for ZNF330 Gene

  • GC04P142719
  • GC04P142499
  • GC04P142361
  • GC04P142142
  • GC04P137871

Summaries for ZNF330 Gene

GeneCards Summary for ZNF330 Gene

ZNF330 (Zinc Finger Protein 330) is a Protein Coding gene.

Gene Wiki entry for ZNF330 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF330 Gene

Genomics for ZNF330 Gene

Regulatory Elements for ZNF330 Gene

Genomic Location for ZNF330 Gene

141,220,887 bp from pter
141,234,697 bp from pter
13,811 bases
Plus strand

Genomic View for ZNF330 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF330 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF330 Gene

Proteins for ZNF330 Gene

  • Protein details for ZNF330 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 330
    Protein Accession:
    Secondary Accessions:
    • B2RDA3

    Protein attributes for ZNF330 Gene

    320 amino acids
    Molecular mass:
    36201 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF330 Gene

Proteomics data for ZNF330 Gene at MOPED

Post-translational modifications for ZNF330 Gene

  • Ubiquitination at Lys44, Lys113, and Lys255
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF330 Gene

Domains for ZNF330 Gene

Gene Families for ZNF330 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF330 Gene


Suggested Antigen Peptide Sequences for ZNF330 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9Y3S2
  • Belongs to the NOA36 family.
genes like me logo Genes that share domains with ZNF330: view

Function for ZNF330 Gene

Gene Ontology (GO) - Molecular Function for ZNF330 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding NAS 10593942
genes like me logo Genes that share ontologies with ZNF330: view

Animal Model Products

CRISPR Products

miRNA for ZNF330 Gene

miRTarBase miRNAs that target ZNF330

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF330

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF330 Gene

Localization for ZNF330 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF330 Gene

Nucleus. Nucleus, nucleolus. Chromosome, centromere. Note=Predominantly expressed in the nucleolus. In mitosis associated with centromeres and concentrated at the midbody in cytokinesis.

Subcellular locations from

Jensen Localization Image for ZNF330 Gene COMPARTMENTS Subcellular localization image for ZNF330 gene
Compartment Confidence
nucleus 5
cytosol 2
cytoskeleton 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ZNF330 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000775 chromosome, centromeric region IDA 10593942
GO:0005634 nucleus --
GO:0005730 nucleolus IDA --
GO:0030496 midbody IDA 10593942
genes like me logo Genes that share ontologies with ZNF330: view

Pathways for ZNF330 Gene

SuperPathways for ZNF330 Gene

No Data Available

Interacting Proteins for ZNF330 Gene

Gene Ontology (GO) - Biological Process for ZNF330 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF330: view

No data available for Pathways by source for ZNF330 Gene

Transcripts for ZNF330 Gene

Unigene Clusters for ZNF330 Gene

Zinc finger protein 330:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF330

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF330 Gene

No ASD Table

Relevant External Links for ZNF330 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF330 Gene

mRNA expression in normal human tissues for ZNF330 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF330 Gene

This gene is overexpressed in Heart - Left Ventricle (4.4).

Protein differential expression in normal tissues for ZNF330 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (33.3) and Islet of Langerhans (6.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF330 Gene

SOURCE GeneReport for Unigene cluster for ZNF330 Gene Hs.120766

mRNA Expression by UniProt/SwissProt for ZNF330 Gene

Tissue specificity: Widely expressed. Higher expression seen in heart and skeletal muscle.
genes like me logo Genes that share expressions with ZNF330: view

Expression partners for ZNF330 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for ZNF330 Gene

Orthologs for ZNF330 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF330 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF330 35
  • 94.48 (n)
  • 98.12 (a)
-- 36
  • 94 (a)
ZNF330 36
  • 98 (a)
(Canis familiaris)
Mammalia ZNF330 35
  • 92.81 (n)
  • 96.87 (a)
ZNF330 36
  • 97 (a)
(Mus musculus)
Mammalia Zfp330 35
  • 89.66 (n)
  • 95.89 (a)
Zfp330 16
Zfp330 36
  • 96 (a)
(Pan troglodytes)
Mammalia ZNF330 35
  • 99.79 (n)
  • 100 (a)
ZNF330 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Zfp330 35
  • 88.64 (n)
  • 96.53 (a)
(Monodelphis domestica)
Mammalia ZNF330 36
  • 92 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF330 36
  • 92 (a)
(Gallus gallus)
Aves ZNF330 35
  • 82.29 (n)
  • 89.69 (a)
ZNF330 36
  • 90 (a)
(Anolis carolinensis)
Reptilia ZNF330 36
  • 88 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.11074 35
znf330 35
  • 77.08 (n)
  • 82.65 (a)
African clawed frog
(Xenopus laevis)
Amphibia noa36-pending-prov 35
(Danio rerio)
Actinopterygii Dr.14880 35
znf330 35
  • 75.71 (n)
  • 84.88 (a)
znf330 36
  • 74 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6501 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008157 35
  • 60.98 (n)
  • 67.05 (a)
fruit fly
(Drosophila melanogaster)
Insecta Noa36 35
  • 62.32 (n)
  • 68.58 (a)
Noa36 36
  • 59 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.5433 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7222 36
  • 67 (a)
Species with no ortholog for ZNF330:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF330 Gene

Gene Tree for ZNF330 (if available)
Gene Tree for ZNF330 (if available)

Paralogs for ZNF330 Gene

No data available for Paralogs for ZNF330 Gene

Variants for ZNF330 Gene

Sequence variations from dbSNP and Humsavar for ZNF330 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs732624 -- 141,230,419(+) AAACA(A/G)AACAG intron-variant
rs1435134 -- 141,232,189(-) GGGAT(A/G)GAGAC intron-variant
rs1897925 -- 141,229,184(+) ATTCA(A/G)TGTAG intron-variant
rs3039631 -- 141,225,536(+) ATAAT(-/AATAAT)TTCAG intron-variant
rs3733484 -- 141,234,364(+) ATTGG(G/T)CTGAT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF330 Gene

Variant ID Type Subtype PubMed ID
dgv1680e1 CNV Complex 17122850

Relevant External Links for ZNF330 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF330 Gene

Disorders for ZNF330 Gene

Relevant External Links for ZNF330

Genetic Association Database (GAD)

No disorders were found for ZNF330 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZNF330 Gene

Publications for ZNF330 Gene

  1. Molecular cloning of a zinc finger autoantigen transiently associated with interphase nucleolus and mitotic centromeres and midbodies. Orthologous proteins with nine CXXC motifs highly conserved from nematodes to humans. (PMID: 10593942) Bolivar J. … Valdivia M.M. (J. Biol. Chem. 1999) 2 3 4
  2. Genomic structure and chromosome location of the human gene encoding the zinc finger autoantigen ZNF330. (PMID: 11528117) BolA-var J. … Valdivia M.M. (Cytogenet. Cell Genet. 2001) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Genome-wide association study of conduct disorder symptomatology. (PMID: 20585324) Dick D.M. … Bierut L. (Mol. Psychiatry 2011) 3 48

Products for ZNF330 Gene

Sources for ZNF330 Gene

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