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Aliases for OR1J2 Gene

Aliases for OR1J2 Gene

  • Olfactory Receptor Family 1 Subfamily J Member 2 2 3 5
  • Olfactory Receptor, Family 1, Subfamily J, Member 2 2 3
  • Olfactory Receptor OR9-19 3 4
  • Olfactory Receptor 1J3 3 4
  • Olfactory Receptor 1J5 3 4
  • HTPCRX15 3 4
  • OST044 3 4
  • OR1J3 3 4
  • OR1J5 3 4
  • HSA5 3 4
  • Olfactory Receptor, Family 1, Subfamily J, Member 3 3
  • Olfactory Receptor, Family 1, Subfamily J, Member 5 3
  • OR9-19 3
  • HG152 3

External Ids for OR1J2 Gene

Previous HGNC Symbols for OR1J2 Gene

  • OR1J3
  • OR1J5

Previous GeneCards Identifiers for OR1J2 Gene

  • GC09U990118
  • GC09P122310
  • GC09P124312
  • GC09P125273

Summaries for OR1J2 Gene

Entrez Gene Summary for OR1J2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1J2 Gene

OR1J2 (Olfactory Receptor Family 1 Subfamily J Member 2) is a Protein Coding gene. Diseases associated with OR1J2 include Stromal Dystrophy. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR1E2.

UniProtKB/Swiss-Prot for OR1J2 Gene

  • Odorant receptor.

Gene Wiki entry for OR1J2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1J2 Gene

Genomics for OR1J2 Gene

Regulatory Elements for OR1J2 Gene

Enhancers for OR1J2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR1J2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR1J2 Gene

122,448,953 bp from pter
122,580,751 bp from pter
131,799 bases
Plus strand

Genomic View for OR1J2 Gene

Genes around OR1J2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1J2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1J2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1J2 Gene

Proteins for OR1J2 Gene

  • Protein details for OR1J2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 1J2
    Protein Accession:
    Secondary Accessions:
    • A3KFL9
    • Q6IF14
    • Q96R90
    • Q9NZP1

    Protein attributes for OR1J2 Gene

    313 amino acids
    Molecular mass:
    35385 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1J2 Gene

Proteomics data for OR1J2 Gene at MOPED

Post-translational modifications for OR1J2 Gene

Other Protein References for OR1J2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1J2 Gene

Domains & Families for OR1J2 Gene

Gene Families for OR1J2 Gene

Protein Domains for OR1J2 Gene

Suggested Antigen Peptide Sequences for OR1J2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1J2: view

Function for OR1J2 Gene

Molecular function for OR1J2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1J2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR1J2: view
genes like me logo Genes that share phenotypes with OR1J2: view

Animal Model Products

CRISPR Products

miRNA for OR1J2 Gene

miRTarBase miRNAs that target OR1J2

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR1J2 Gene

Localization for OR1J2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1J2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR1J2 Gene COMPARTMENTS Subcellular localization image for OR1J2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1J2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR1J2: view

Pathways & Interactions for OR1J2 Gene

genes like me logo Genes that share pathways with OR1J2: view

Pathways by source for OR1J2 Gene

Interacting Proteins for OR1J2 Gene

Gene Ontology (GO) - Biological Process for OR1J2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1J2: view

No data available for SIGNOR curated interactions for OR1J2 Gene

Drugs & Compounds for OR1J2 Gene

No Compound Related Data Available

Transcripts for OR1J2 Gene

mRNA/cDNA for OR1J2 Gene

(2) REFSEQ mRNAs :
(9) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1J2 Gene

No ASD Table

Relevant External Links for OR1J2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR1J2 Gene

mRNA expression in normal human tissues for OR1J2 Gene

mRNA differential expression in normal tissues according to GTEx for OR1J2 Gene

This gene is overexpressed in Testis (x11.3).

Protein differential expression in normal tissues from HIPED for OR1J2 Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR1J2 Gene

SOURCE GeneReport for Unigene cluster for OR1J2 Gene Hs.460145

genes like me logo Genes that share expression patterns with OR1J2: view

Protein tissue co-expression partners for OR1J2 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for OR1J2 Gene

Orthologs for OR1J2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1J2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR1J2 35
  • 86.28 (n)
  • 84.57 (a)
OR1J2 36
  • 84 (a)
(Mus musculus)
Mammalia Olfr348 35
  • 73.7 (n)
  • 71.1 (a)
Olfr348 16
Olfr346 36
  • 71 (a)
(Pan troglodytes)
Mammalia LOC473040 35
  • 99.68 (n)
  • 99.68 (a)
PTR212 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Olr409 35
  • 73.68 (n)
  • 71.84 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 74 (a)
Species with no ortholog for OR1J2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1J2 Gene

Gene Tree for OR1J2 (if available)
Gene Tree for OR1J2 (if available)

Paralogs for OR1J2 Gene

(456) SIMAP similar genes for OR1J2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR1J2: view

Variants for OR1J2 Gene

Sequence variations from dbSNP and Humsavar for OR1J2 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs4836891 - 122,511,295(+) GACCC(A/G)GCTGT intron-variant, reference, missense
rs41277120 - 122,511,156(+) CAATG(A/G/T)CATAT intron-variant, reference, missense
rs1004678 -- 122,465,188(-) AGACT(A/G)GCAGG intron-variant
rs1004679 -- 122,464,994(-) GAAAA(A/G)AATCA intron-variant
rs1041356 -- 122,542,471(+) tgccc(C/T)gtatt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR1J2 Gene

Variant ID Type Subtype PubMed ID
nsv893822 CNV Gain 21882294
nsv893823 CNV Loss 21882294

Variation tolerance for OR1J2 Gene

Residual Variation Intolerance Score: 68.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.79; 79.05% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR1J2 Gene

Disorders for OR1J2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for OR1J2 Gene - From: DISEASES

Disorder Aliases PubMed IDs
stromal dystrophy
- elite association - COSMIC cancer census association via MalaCards
Search OR1J2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for OR1J2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with OR1J2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OR1J2 Gene

Publications for OR1J2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Natural selection on the olfactory receptor gene family in humans and chimpanzees. (PMID: 12908129) Gilad Y. … Paabo S. (Am. J. Hum. Genet. 2003) 3
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  5. The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. (PMID: 10706615) Rouquier S. … Giorgi D. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3

Products for OR1J2 Gene

Sources for OR1J2 Gene