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Aliases for OR7C1 Gene

Aliases for OR7C1 Gene

  • Olfactory Receptor, Family 7, Subfamily C, Member 1 2 3
  • Olfactory Receptor OR19-16 3 4
  • Olfactory Receptor TPCR86 3 4
  • Olfactory Receptor 7C4 3 4
  • OR7C4 3 4
  • Olfactory Receptor, Family 7, Subfamily C, Member 4 3
  • Olfactory Receptor 7C1 3
  • CIT-HSP-146E8 3
  • HSTPCR86P 3
  • OR19-5 3
  • TPCR86 3

External Ids for OR7C1 Gene

Previous HGNC Symbols for OR7C1 Gene

  • OR7C4

Previous GeneCards Identifiers for OR7C1 Gene

  • GC19M015278
  • GC19M015330
  • GC19M014782
  • GC19M014770
  • GC19M014909

Summaries for OR7C1 Gene

Entrez Gene Summary for OR7C1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7C1 Gene

OR7C1 (Olfactory Receptor, Family 7, Subfamily C, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7G1.

UniProtKB/Swiss-Prot for OR7C1 Gene

  • Odorant receptor.

Gene Wiki entry for OR7C1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7C1 Gene

Genomics for OR7C1 Gene

Regulatory Elements for OR7C1 Gene

Genomic Location for OR7C1 Gene

Start:
14,799,131 bp from pter
End:
14,835,376 bp from pter
Size:
36,246 bases
Orientation:
Minus strand

Genomic View for OR7C1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR7C1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7C1 Gene

Proteins for OR7C1 Gene

  • Protein details for OR7C1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O76099-OR7C1_HUMAN
    Recommended name:
    Olfactory receptor 7C1
    Protein Accession:
    O76099
    Secondary Accessions:
    • Q15621
    • Q6IFP2
    • Q96R94

    Protein attributes for OR7C1 Gene

    Size:
    320 amino acids
    Molecular mass:
    35519 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7C1 Gene

Proteomics data for OR7C1 Gene at MOPED

Post-translational modifications for OR7C1 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR7C1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR7C1 Gene

Domains for OR7C1 Gene

Gene Families for OR7C1 Gene

HGNC:
  • OR7 :GPCR / Class A : Olfactory receptors

Protein Domains for OR7C1 Gene

Suggested Antigen Peptide Sequences for OR7C1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O76099

UniProtKB/Swiss-Prot:

OR7C1_HUMAN :
  • O76099
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7C1: view

Function for OR7C1 Gene

Molecular function for OR7C1 Gene

GENATLAS Biochemistry:
olfactory receptor,family 7,subfamily C,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR7C1: view

Phenotypes for OR7C1 Gene

GenomeRNAi human phenotypes for OR7C1:
genes like me logo Genes that share phenotypes with OR7C1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR7C1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR7C1 Gene

Localization for OR7C1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7C1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR7C1 Gene COMPARTMENTS Subcellular localization image for OR7C1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR7C1: view

Pathways for OR7C1 Gene

genes like me logo Genes that share pathways with OR7C1: view

Pathways by source for OR7C1 Gene

1 KEGG pathway for OR7C1 Gene

Interacting Proteins for OR7C1 Gene

Gene Ontology (GO) - Biological Process for OR7C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007283 spermatogenesis TAS 9268701
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7C1: view

Transcripts for OR7C1 Gene

mRNA/cDNA for OR7C1 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7C1 Gene

Olfactory receptor, family 7, subfamily C, member 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR7C1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR7C1 Gene

No ASD Table

Relevant External Links for OR7C1 Gene

GeneLoc Exon Structure for
OR7C1
ECgene alternative splicing isoforms for
OR7C1

Expression for OR7C1 Gene

mRNA expression in normal human tissues for OR7C1 Gene

mRNA differential expression in normal tissues according to GTEx for OR7C1 Gene

This gene is overexpressed in Pituitary (9.3), Testis (9.2), Skin - Sun Exposed (Lower leg) (4.4), and Adrenal Gland (4.1).

Protein differential expression in normal tissues for OR7C1 Gene

This gene is overexpressed in Cerebrospinal fluid (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR7C1 Gene

SOURCE GeneReport for Unigene cluster for OR7C1 Gene Hs.466053

genes like me logo Genes that share expressions with OR7C1: view

Expression partners for OR7C1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for OR7C1 Gene

Orthologs for OR7C1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7C1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR7A10 35
  • 74.11 (n)
  • 69.58 (a)
-- 36
  • 68 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia LOC102151861 35
  • 74.63 (n)
  • 65.61 (a)
-- 36
  • 79 (a)
OneToMany
OR10D01 36
  • 78 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr1352 35
  • 67.98 (n)
  • 64.92 (a)
Olfr371 36
  • 69 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC748178 35
  • 98.12 (n)
  • 96.87 (a)
OR7C1 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr1077 35
  • 69.18 (n)
  • 64.92 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 67 (a)
ManyToMany
-- 36
  • 66 (a)
ManyToMany
-- 36
  • 65 (a)
ManyToMany
-- 36
  • 67 (a)
ManyToMany
-- 36
  • 62 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 62 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 67 (a)
ManyToMany
OPOR13 36
  • 61 (a)
ManyToMany
OPOR142 36
  • 63 (a)
ManyToMany
OPOR17 36
  • 65 (a)
ManyToMany
OPOR20 36
  • 67 (a)
ManyToMany
OPOR21 36
  • 63 (a)
ManyToMany
OPOR24 36
  • 64 (a)
ManyToMany
OPOR9 36
  • 65 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 61 (a)
ManyToMany
-- 36
  • 59 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 60 (a)
ManyToMany
Species with no ortholog for OR7C1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7C1 Gene

ENSEMBL:
Gene Tree for OR7C1 (if available)
TreeFam:
Gene Tree for OR7C1 (if available)

Paralogs for OR7C1 Gene

Paralogs for OR7C1 Gene

Selected SIMAP similar genes for OR7C1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR7C1 Gene

genes like me logo Genes that share paralogs with OR7C1: view

Variants for OR7C1 Gene

Sequence variations from dbSNP and Humsavar for OR7C1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs962545 -- 14,811,376(+) CCTCT(C/G)TCTGT intron-variant
rs2041101 -- 14,801,162(+) TCACC(C/T)TTGTT upstream-variant-2KB, intron-variant
rs2041102 -- 14,801,240(+) CTTTT(C/T)CCCCC upstream-variant-2KB, intron-variant
rs2041103 -- 14,801,339(+) GCAAA(C/T)ATCTG upstream-variant-2KB, intron-variant
rs2041104 -- 14,801,505(+) ACTGC(A/G)TATTA upstream-variant-2KB, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR7C1 Gene

Variant ID Type Subtype PubMed ID
nsv509722 CNV Insertion 20534489

Relevant External Links for OR7C1 Gene

HapMap Linkage Disequilibrium report
OR7C1
Human Gene Mutation Database (HGMD)
OR7C1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR7C1 Gene

Disorders for OR7C1 Gene

No disorders were found for OR7C1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR7C1 Gene

Publications for OR7C1 Gene

  1. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P. … Parmentier M. (Genomics 1997) 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR7C1 Gene

Sources for OR7C1 Gene

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