Aliases for GC Gene
External Ids for GC Gene
Previous GeneCards Identifiers for GC Gene
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
GeneCards Summary for GC Gene
GC (Group-Specific Component (Vitamin D Binding Protein)) is a Protein Coding gene. Diseases associated with GC include graves' disease and central nervous system disease. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include actin binding and vitamin transporter activity. An important paralog of this gene is AFM.
UniProtKB/Swiss-Prot for GC Gene
Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes