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Aliases for DHRS7B Gene

Aliases for DHRS7B Gene

  • Dehydrogenase/Reductase (SDR Family) Member 7B 2 3
  • Short-Chain Dehydrogenase/Reductase Family 32C Member 1 3 4
  • SDR32C1 3 4
  • Short Chain Dehydrogenase/Reductase Family 32C, Member 1 3
  • Short Chain Dehydrogenase/Reductase Family 32C 2
  • Dehydrogenase/Reductase SDR Family Member 7B 3
  • EC 1.1.-.- 4
  • Member 1 2
  • CGI-93 3

External Ids for DHRS7B Gene

Previous GeneCards Identifiers for DHRS7B Gene

  • GC17P020971
  • GC17P021030
  • GC17P020232
  • GC17P021269
  • GC17P021531
  • GC17P022221

Summaries for DHRS7B Gene

Entrez Gene Summary for DHRS7B Gene

  • This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

GeneCards Summary for DHRS7B Gene

DHRS7B (Dehydrogenase/Reductase (SDR Family) Member 7B) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity. An important paralog of this gene is HSD11B2.

UniProtKB/Swiss-Prot for DHRS7B Gene

  • Putative oxidoreductase.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DHRS7B Gene

Genomics for DHRS7B Gene

Regulatory Elements for DHRS7B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for DHRS7B Gene

21,123,364 bp from pter
21,193,265 bp from pter
69,902 bases
Plus strand

Genomic View for DHRS7B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DHRS7B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DHRS7B Gene

Proteins for DHRS7B Gene

  • Protein details for DHRS7B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Dehydrogenase/reductase SDR family member 7B
    Protein Accession:
    Secondary Accessions:
    • B5MEF4
    • Q6UX59
    • Q9BTF9
    • Q9UFM6
    • Q9Y3A1

    Protein attributes for DHRS7B Gene

    325 amino acids
    Molecular mass:
    35119 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAD34088.1; Type=Frameshift; Positions=12, 266; Evidence={ECO:0000305}; Sequence=AAQ88862.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for DHRS7B Gene

Proteomics data for DHRS7B Gene at MOPED

Post-translational modifications for DHRS7B Gene

  • Ubiquitination at Lys183
  • Modification sites at PhosphoSitePlus

Other Protein References for DHRS7B Gene

Antibody Products

No data available for DME Specific Peptides for DHRS7B Gene

Domains for DHRS7B Gene

Gene Families for DHRS7B Gene

  • SDRC3 :Short chain dehydrogenase/reductase superfamily / Classical SDR fold cluster 3

Suggested Antigen Peptide Sequences for DHRS7B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q6IAN0
  • Belongs to the short-chain dehydrogenases/reductases (SDR) family.
genes like me logo Genes that share domains with DHRS7B: view

Function for DHRS7B Gene

Molecular function for DHRS7B Gene

UniProtKB/Swiss-Prot Function:
Putative oxidoreductase.

Enzyme Numbers (IUBMB) for DHRS7B Gene

Gene Ontology (GO) - Molecular Function for DHRS7B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with DHRS7B: view
genes like me logo Genes that share phenotypes with DHRS7B: view

Animal Model Products

miRNA for DHRS7B Gene

miRTarBase miRNAs that target DHRS7B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DHRS7B

In Situ Assay Products

Flow Cytometry Products

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for DHRS7B Gene

Localization for DHRS7B Gene

Subcellular locations from UniProtKB/Swiss-Prot for DHRS7B Gene

Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Subcellular locations from

Jensen Localization Image for DHRS7B Gene COMPARTMENTS Subcellular localization image for DHRS7B gene
Compartment Confidence
peroxisome 5
golgi apparatus 3
nucleus 3
plasma membrane 3

Gene Ontology (GO) - Cellular Components for DHRS7B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum --
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0016020 membrane IDA 19946888
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DHRS7B: view

Pathways for DHRS7B Gene

SuperPathways for DHRS7B Gene

No Data Available

Interacting Proteins for DHRS7B Gene

Gene Ontology (GO) - Biological Process for DHRS7B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
GO:0008152 metabolic process --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with DHRS7B: view

No data available for Pathways by source for DHRS7B Gene

Transcripts for DHRS7B Gene

Unigene Clusters for DHRS7B Gene

Dehydrogenase/reductase (SDR family) member 7B:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DHRS7B

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DHRS7B Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b
SP1: - - - - -
SP2: - - - - - - -
SP4: - - -
SP5: - -
SP6: - - -
SP7: -

Relevant External Links for DHRS7B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DHRS7B Gene

mRNA expression in normal human tissues for DHRS7B Gene

Protein differential expression in normal tissues for DHRS7B Gene

This gene is overexpressed in Nasal epithelium (60.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DHRS7B Gene

SOURCE GeneReport for Unigene cluster for DHRS7B Gene Hs.386989

genes like me logo Genes that share expressions with DHRS7B: view

Expression partners for DHRS7B Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for DHRS7B Gene

Orthologs for DHRS7B Gene

This gene was present in the common ancestor of animals.

Orthologs for DHRS7B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia DHRS7B 35
  • 81.74 (n)
  • 81.23 (a)
  • 81 (a)
(Canis familiaris)
Mammalia DHRS7B 35
  • 86.52 (n)
  • 87.35 (a)
  • 81 (a)
(Mus musculus)
Mammalia Dhrs7b 35
  • 82.46 (n)
  • 78.02 (a)
Dhrs7b 16
Dhrs7b 36
  • 78 (a)
(Pan troglodytes)
Mammalia DHRS7B 35
  • 99.49 (n)
  • 99.08 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Dhrs7b 35
  • 81.23 (n)
  • 77.54 (a)
(Monodelphis domestica)
Mammalia DHRS7B 36
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia DHRS7B 36
  • 69 (a)
(Gallus gallus)
Aves DHRS7B 35
  • 71.3 (n)
  • 71.6 (a)
  • 72 (a)
(Anolis carolinensis)
Reptilia DHRS7B 36
  • 59 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia dhrs7b 35
  • 66.24 (n)
  • 67.96 (a)
Str.1806 35
(Danio rerio)
Actinopterygii dhrs7b 35
  • 61.51 (n)
  • 57.57 (a)
Dr.14424 35
dhrs7b 36
  • 57 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5249 35
African malaria mosquito
(Anopheles gambiae)
Insecta DHRS7_ANOGA 35
  • 52.4 (n)
  • 49.16 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7601 35
  • 51.55 (n)
  • 46.03 (a)
CG7601 36
  • 43 (a)
(Caenorhabditis elegans)
Secernentea dhs-30 35
  • 49.23 (n)
  • 41.34 (a)
C33E10.10 36
  • 32 (a)
dhs-30 36
  • 37 (a)
T25G12.13 36
  • 35 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
Species with no ortholog for DHRS7B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DHRS7B Gene

Gene Tree for DHRS7B (if available)
Gene Tree for DHRS7B (if available)

Paralogs for DHRS7B Gene

Selected SIMAP similar genes for DHRS7B Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with DHRS7B: view

Variants for DHRS7B Gene

Sequence variations from dbSNP and Humsavar for DHRS7B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs1448 -- 21,185,027(-) AATCA(A/G)TTATG intron-variant
rs899331 -- 21,167,211(+) CTGCA(C/T)AAATG intron-variant
rs899332 -- 21,169,029(+) TCATC(C/T)TGCTC intron-variant
rs899333 -- 21,169,050(+) GTGAA(A/G)ACGGG intron-variant
rs999187 -- 21,166,999(+) TTTTT(A/G)TTAAC intron-variant

Relevant External Links for DHRS7B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for DHRS7B Gene

Disorders for DHRS7B Gene

No disorders were found for DHRS7B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for DHRS7B Gene

Publications for DHRS7B Gene

  1. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PMID: 19027726) Persson B. … Oppermann U. (Chem. Biol. Interact. 2009) 2 3 4
  2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4
  3. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for DHRS7B Gene

Sources for DHRS7B Gene

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