Aliases for RCHY1 Gene
Aliases for RCHY1 Gene
- Ring Finger And CHY Zinc Finger Domain Containing 1 2 3 5
- Zinc Finger Protein 363 2 3 4
- Ring Finger And CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase 2 3
- Androgen-Receptor N-Terminal-Interacting Protein 2 3
- P53-Induced Protein With A RING-H2 Domain 2 3
- RING-Type E3 Ubiquitin Transferase RCHY1 3 4
- E3 Ubiquitin-Protein Ligase Pirh2 3 4
- RING Finger Protein 199 3 4
- Zinc Finger, CHY-Type 2 3
- ZNF363 3 4
- RNF199 3 4
- ARNIP 3 4
External Ids for RCHY1 Gene
- HGNC: 17479
- Entrez Gene: 25898
- Ensembl: ENSG00000163743
- OMIM: 607680
- UniProtKB: Q96PM5
Previous HGNC Symbols for RCHY1 Gene
- ZNF363
Previous GeneCards Identifiers for RCHY1 Gene
- GC04M076866
- GC04M076762
- GC04M076623
- GC04M076405
- GC04M072150
Summaries for RCHY1 Gene
-
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]
GeneCards Summary for RCHY1 Gene
RCHY1 (Ring Finger And CHY Zinc Finger Domain Containing 1) is a Protein Coding gene. Diseases associated with RCHY1 include Variola Minor. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include protein homodimerization activity and ligase activity.
UniProtKB/Swiss-Prot for RCHY1 Gene
-
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RCHY1 Gene
Genomics for RCHY1 Gene
Regulatory Elements for RCHY1 Gene
Enhancers for RCHY1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH04G075511 | 1.4 | ENCODE dbSUPER | 17.1 | +0.9 | 943 | 4.9 | HDGF PKNOX1 MLX CREB3L1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 | RCHY1 THAP6 |
| GH04G076233 | 1.7 | Ensembl ENCODE dbSUPER | 9.7 | -721.2 | -721155 | 5.5 | CREB3L1 MLX DMAP1 FEZF1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 | FAM47E RPL7P17 SCARB2 THAP6 RCHY1 ENSG00000251185 STBD1 LOC105377286 |
| GH04G075847 | 0.6 | ENCODE | 11.2 | -332.9 | -332859 | 0.2 | ZNF426 ZNF394 ZBTB8A ZNF433 ZNF781 ZNF518A ZNF101 | THAP6 SDAD1 LOC105377284 PPEF2 RCHY1 GC04P075831 LOC105377285 |
| GH04G075494 | 0.4 | Ensembl | 16.2 | +20.1 | 20060 | 0.6 | BCL6B CEBPB | RCHY1 THAP6 GC04M075464 |
| GH04G075561 | 0.8 | ENCODE | 5.6 | -47.2 | -47167 | 1.3 | PKNOX1 TEAD4 SIN3A MAX RBBP5 RAD21 YY1 CTBP1 GATA3 ZNF687 | C4orf26 RCHY1 CDKL2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RCHY1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the RCHY1 gene promoter:
Regulatory Element Products
Genomic Location for RCHY1 Gene
- Chromosome:
- 4
- Start:
- 75,479,037 bp from pter
- End:
- 75,514,764 bp from pter
- Size:
- 35,728 bases
- Orientation:
- Minus strand
Genomic View for RCHY1 Gene
Genes around RCHY1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q21.1 by Ensembl
- 4q21.1 by Entrez Gene
- 4q21.1 by HGNC
RCHY1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RCHY1 Gene
Proteins for RCHY1 Gene
-
Protein details for RCHY1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96PM5-ZN363_HUMAN
- Recommended name:
- RING finger and CHY zinc finger domain-containing protein 1
- Protein Accession:
- Q96PM5
- B3KRG3
- C7E541
- C7E542
- C7E543
- D3YRV2
- E7EMC8
- E7ETW5
- J3KPI0
- Q2KN33
- Q59GN7
- Q86X26
- Q96PR5
Protein attributes for RCHY1 Gene
- Size:
- 261 amino acids
- Molecular mass:
- 30110 Da
- Quaternary structure:
-
- Monomer and homodimer. Interacts with AR, p53/TP53, MDM2, HDAC1, KAT5, PLAG1, PLAGL2, CDKN1B, COPE, UBE2D2 and GORAB/NTKLBP1.
- SequenceCaution:
-
- Sequence=BAD92309.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for RCHY1 Gene
Post-translational modifications for RCHY1 Gene
- Subject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability.
- Ubiquitination at Lys241
- Modification sites at PhosphoSitePlus
Other Protein References for RCHY1 Gene
Antibody Products
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-
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- antibodies-online Antibodies for RCHY1: See all 47
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-
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Protein Products
-
OriGene Purified Proteins for RCHY1
- Search Origene for MassSpec and Protein Over-expression Lysates for RCHY1
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- antibodies-online Proteins for RCHY1: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Proteins for RCHY1
No data available for DME Specific Peptides for RCHY1 Gene
Domains & Families for RCHY1 Gene
Gene Families for RCHY1 Gene
Protein Domains for RCHY1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RCHY1 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for RCHY1 Gene
Function for RCHY1 Gene
Molecular function for RCHY1 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
- UniProtKB/Swiss-Prot Function:
- Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated during the S phase of the cell cycle. Expressed at low levels during G phase.
Enzyme Numbers (IUBMB) for RCHY1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002039 | p53 binding | IPI | 19043414 |
| GO:0004842 | ubiquitin-protein transferase activity | TAS | -- |
| GO:0005102 | receptor binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 15781263 |
| GO:0008270 | zinc ion binding | IDA,IEA | 19043414 |
Phenotypes for RCHY1 Gene
- MGI mutant phenotypes for RCHY1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RCHY1:
Animal Models for RCHY1 Gene
- MGI Knock Outs for RCHY1:
-
- Rchy1 tm1.1Raz
Animal Model Products
-
Taconic Biosciences Mouse Models for RCHY1
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-
-
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-
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CRISPR Products
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miRNA for RCHY1 Gene
- miRTarBase miRNAs that target RCHY1
miRNA Products
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-
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for RCHY1
-
ViGene Biosciences adenoviral particle packaged cDNA for RCHY1 gene
-
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-
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No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RCHY1 Gene
Localization for RCHY1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RCHY1 Gene
- Nucleus. Nucleus speckle. Cytoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 2 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000151 | ubiquitin ligase complex | IDA | 19043414 |
| GO:0005634 | nucleus | IDA,IEA | 19483087 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IDA | 15781263 |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for RCHY1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | ||
| 3 | Influenza A |
.34
|
|
| 4 | DNA Damage Response | ||
| 5 | Ubiquitin mediated proteolysis | ||
Pathways by source for RCHY1 Gene
1 Cell Signaling Technology pathway for RCHY1 Gene
3 BioSystems pathways for RCHY1 Gene
3 KEGG pathways for RCHY1 Gene
1 R&D Systems pathway for RCHY1 Gene
UniProtKB/Swiss-Prot Q96PM5-ZN363_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for RCHY1 Gene
Selected Interacting proteins:
ENSP00000321239
Q96PM5-ZN363_HUMAN
for RCHY1 Gene via
STRING
MINT
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016567 | protein ubiquitination | IDA,IEA | 19043414 |
| GO:0031398 | positive regulation of protein ubiquitination | IDA | 19483087 |
| GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IDA | 19483087 |
| GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | 19483087 |
| GO:0070987 | error-free translesion synthesis | TAS | -- |
Transcripts for RCHY1 Gene
mRNA/cDNA for RCHY1 Gene
- (9) REFSEQ mRNAs :
- (20) Additional mRNA sequences :
- (175) Selected AceView cDNA sequences:
- (13) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RCHY1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for RCHY1
-
Santa Cruz Biotechnology (SCBT) CRISPR for RCHY1
- GenScript: Design CRISPR guide RNA sequences for RCHY1
miRNA Products
- Search ViGene Biosciences for RCHY1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for RCHY1
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-
ViGene Biosciences ready-to-package AAV shRNAs for RCHY1 gene
Clone Products
- Sino Biological Human cDNA Clone for RCHY1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for RCHY1
- VectorBuilder custom plasmid, inducible vectors for RCHY1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RCHY1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||
| SP5: | - |
Expression for RCHY1 Gene
This gene is overexpressed in NK cells (15.5), Peripheral blood mononuclear cells (13.6), and Fetal ovary (9.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RCHY1 Gene
NURSA nuclear receptor signaling pathways regulating expression of RCHY1 Gene:
RCHY1SOURCE GeneReport for Unigene cluster for RCHY1 Gene:
Hs.48297Evidence on tissue expression from TISSUES for RCHY1 Gene
- Nervous system(4.8)
- Blood(4.3)
- Kidney(2.5)
- Heart(2.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for RCHY1
-
OriGene qPCR primer pairs for RCHY1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RCHY1 Gene
Orthologs for RCHY1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RCHY1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | RCHY1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | RCHY1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Rchy1 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | RCHY1 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Rchy1 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | RCHY1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RCHY1 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rchy1 34 |
|
||
| Str.10607 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | rchy1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG16947 35 34 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT3G62970 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os12g0538500 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.11347 35 |
|
OneToOne |
- Species where no ortholog for RCHY1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for RCHY1 Gene
(1) SIMAP similar genes for RCHY1 Gene using alignment to 7 proteins:
No data available for Paralogs for RCHY1 Gene
Variants for RCHY1 Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000067470 | -- | 75,503,686(+) | ACTCC(-/A)ATCTC | intron-variant | |
| rs1000096697 | -- | 75,503,989(+) | ATGAA(G/T)AAAGG | intron-variant | |
| rs1000234603 | -- | 75,478,554(+) | CGTTG(A/G)GAATG | downstream-variant-500B | |
| rs1000253883 | -- | 75,510,787(+) | GTAAC(A/C)AACTC | intron-variant | |
| rs1000365525 | -- | 75,511,059(+) | GTATC(A/G)AGGAA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1111276 | CNV | tandem duplication | 24896259 |
| nsv1131809 | CNV | deletion | 24896259 |
| nsv1140180 | CNV | insertion | 24896259 |
| nsv1143097 | CNV | tandem duplication | 24896259 |
| nsv594687 | CNV | loss | 21841781 |
| nsv7363 | OTHER | inversion | 18451855 |
Residual Variation Intolerance Score:
30.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.42;
9.20% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for RCHY1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RCHY1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RCHY1 Gene
Disorders for RCHY1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| variola minor |
|
|
Search RCHY1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for RCHY1
No data available for UniProtKB/Swiss-Prot and Genatlas for RCHY1 Gene
Publications for RCHY1 Gene
- Molecular basis of Pirh2-mediated p53 ubiquitylation. (PMID: 19043414) Sheng Y. … Arrowsmith C.H. (Nat. Struct. Mol. Biol. 2008) 3 4 22 64
- PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53. (PMID: 17950244) Zheng G. … Yang Y.-C. (Biochem. Biophys. Res. Commun. 2007) 3 4 22 64
- Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome. (PMID: 14701804) Logan I.R. … Robson C.N. (J. Biol. Chem. 2004) 3 4 22 64
- Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. (PMID: 12654245) Leng R.P. … Benchimol S. (Cell 2003) 2 3 22 64
- Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. (PMID: 22491018) Wang J. … Platt A. (Pharmacogenomics J. 2013) 3 46 64
Products for RCHY1 Gene
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- Horizon Cell Lines for RCHY1
- Cyagen custom Knockout/knockin (KOKI) mouse models for RCHY1
- VectorBuilder custom plasmid, inducible vectors for RCHY1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RCHY1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RCHY1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer