Aliases for RCHY1 Gene
Aliases for RCHY1 Gene
- Ring Finger And CHY Zinc Finger Domain Containing 1 2 3 5
- ZNF363 2 3 4
- Androgen-Receptor N-Terminal-Interacting Protein 2 3
- P53-Induced Protein With A RING-H2 Domain 2 3
- RING-Type E3 Ubiquitin Transferase RCHY1 3 4
- E3 Ubiquitin-Protein Ligase Pirh2 3 4
- Zinc Finger Protein 363 3 4
- RING Finger Protein 199 3 4
- Zinc Finger, CHY-Type 2 3
- RNF199 3 4
- ARNIP 3 4
- CHIMP 3 4
- PIRH2 3 4
- Ring Finger And CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase 3
- RING Finger And CHY Zinc Finger Domain-Containing Protein 1 3
- Androgen Receptor N-Terminal-Interacting Protein 4
- CH-Rich Interacting Match With PLAG1 3
- CH-Rich-Interacting Match With PLAG1 4
- P53-Induced RING-H2 Protein 4
- EC 2.3.2.27 4
- PRO1996 3
- HPirh2 4
- ZCHY 3
External Ids for RCHY1 Gene
- HGNC: 17479
- Entrez Gene: 25898
- Ensembl: ENSG00000163743
- OMIM: 607680
- UniProtKB: Q96PM5
Previous HGNC Symbols for RCHY1 Gene
- ZNF363
Previous GeneCards Identifiers for RCHY1 Gene
- GC04M076866
- GC04M076762
- GC04M076623
- GC04M076405
- GC04M072150
Summaries for RCHY1 Gene
-
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]
GeneCards Summary for RCHY1 Gene
RCHY1 (Ring Finger And CHY Zinc Finger Domain Containing 1) is a Protein Coding gene. Diseases associated with RCHY1 include Variola Minor. Among its related pathways are Innate Immune System and Direct p53 effectors. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and ligase activity.
UniProtKB/Swiss-Prot for RCHY1 Gene
-
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
Additional gene information for RCHY1 Gene
- Monarch Initiative
- Search for RCHY1 at DataMed
- Search for RCHY1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RCHY1 Gene
Genomics for RCHY1 Gene
GeneHancer (GH) Regulatory Elements for RCHY1 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH04I075511 | Promoter/Enhancer | 2.3 | EPDnew Ensembl ENCODE dbSUPER | 567.1 | +0.9 | 943 | 4.9 | HDGF PKNOX1 CLOCK FOXA2 SMAD1 MLX ARNT ZFP64 ARID4B SIN3A | THAP6 RCHY1 NUP54 | |
GH04I076192 | Enhancer | 1.5 | Ensembl ENCODE dbSUPER | 11.2 | -683.0 | -683029 | 9.7 | HDGF PKNOX1 FOXA2 SMAD1 MLX ARID4B FEZF1 YBX1 ZNF2 IRF4 | NUP54 SCARB2 RCHY1 THAP6 ART3 NAAA GC04P076210 | |
GH04I075494 | Enhancer | 0.4 | Ensembl | 16.2 | +20.1 | 20059 | 0.6 | BCL6B CEBPB | RCHY1 THAP6 GC04M075464 | |
GH04I075847 | Enhancer | 0.5 | ENCODE | 11.2 | -332.9 | -332859 | 0.2 | ZBTB8A ZNF433 ZNF781 ZNF518A | THAP6 LOC105377284 PPEF2 RCHY1 SDAD1 GC04P075831 LOC105377285 | |
GH04I075561 | Enhancer | 0.7 | ENCODE | 5.6 | -47.2 | -47166 | 1.3 | PKNOX1 NEUROD1 SIN3A RFX5 CTBP1 GATA3 SMARCE1 ZNF687 NRF1 CEBPB | ODAPH RCHY1 CDKL2 |
Regulatory Element Products
Genomic Locations for RCHY1 Gene
- chr4:75,479,037-75,514,764
- (GRCh38/hg38)
- Size:
- 35,728 bases
- Orientation:
- Minus strand
- chr4:76,404,247-76,439,974
- (GRCh37/hg19)
Genomic View for RCHY1 Gene
- Cytogenetic band:
-
- 4q21.1 by Ensembl
- 4q21.1 by Entrez Gene
- 4q21.1 by HGNC


RefSeq DNA sequence for RCHY1 Gene
Proteins for RCHY1 Gene
-
Protein details for RCHY1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96PM5-ZN363_HUMAN
- Recommended name:
- RING finger and CHY zinc finger domain-containing protein 1
- Protein Accession:
- Q96PM5
- B3KRG3
- C7E541
- C7E542
- C7E543
- D3YRV2
- E7EMC8
- E7ETW5
- J3KPI0
- Q2KN33
- Q59GN7
- Q86X26
- Q96PR5
Protein attributes for RCHY1 Gene
- Size:
- 261 amino acids
- Molecular mass:
- 30110 Da
- Quaternary structure:
-
- Monomer and homodimer. Interacts with AR, p53/TP53, MDM2, HDAC1, KAT5, PLAG1, PLAGL2, CDKN1B, COPE, UBE2D2 and GORAB/NTKLBP1.
- SequenceCaution:
-
- Sequence=BAD92309.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for RCHY1 Gene
Post-translational modifications for RCHY1 Gene
- Subject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability.
- Ubiquitination at isoforms=2, 6, 7, 8241
Other Protein References for RCHY1 Gene
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Assay Products
No data available for DME Specific Peptides for RCHY1 Gene
Domains & Families for RCHY1 Gene
Gene Families for RCHY1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for RCHY1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RCHY1 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for RCHY1 Gene
Function for RCHY1 Gene
Molecular function for RCHY1 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
- UniProtKB/Swiss-Prot Function:
- Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated during the S phase of the cell cycle. Expressed at low levels during G phase.
Enzyme Numbers (IUBMB) for RCHY1 Gene
Phenotypes From GWAS Catalog for RCHY1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002039 | p53 binding | IPI | 19043414 |
GO:0004842 | ubiquitin-protein transferase activity | TAS | -- |
GO:0005102 | receptor binding | IEA | -- |
GO:0005515 | protein binding | IPI | 15781263 |
GO:0008270 | zinc ion binding | IEA,IDA | 19043414 |
Phenotypes for RCHY1 Gene
- MGI mutant phenotypes for RCHY1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RCHY1:
Animal Models for RCHY1 Gene
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-
- Rchy1 tm1.1Raz
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No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RCHY1 Gene
Localization for RCHY1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RCHY1 Gene
- Nucleus. Nucleus speckle. Cytoplasm.
- Cytosol (3)
- Nucleoplasm (3)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000151 | ubiquitin ligase complex | IDA | 19043414 |
GO:0005634 | nucleus | IDA,IEA | 19483087 |
GO:0005654 | nucleoplasm | TAS | -- |
GO:0005737 | cytoplasm | IDA | 15781263 |
GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for RCHY1 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Class I MHC mediated antigen processing and presentation | ||
2 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | ||
3 | Influenza A |
.34
|
|
4 | DNA Damage Response | ||
5 | Ubiquitin mediated proteolysis |
Pathways by source for RCHY1 Gene
1 Cell Signaling Technology pathway for RCHY1 Gene
3 BioSystems pathways for RCHY1 Gene
8 Reactome pathways for RCHY1 Gene
3 KEGG pathways for RCHY1 Gene
UniProtKB/Swiss-Prot Q96PM5-ZN363_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for RCHY1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016567 | protein ubiquitination | IEA,IDA | 19043414 |
GO:0031398 | positive regulation of protein ubiquitination | IDA | 19483087 |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IDA | 19483087 |
GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | 19483087 |
GO:0070987 | error-free translesion synthesis | TAS | -- |
Transcripts for RCHY1 Gene
mRNA/cDNA for RCHY1 Gene
- (9) REFSEQ mRNAs :
- (20) Additional mRNA sequences :
- (175) Selected AceView cDNA sequences:
- (13) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RCHY1 Gene
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||||||||
SP2: | - | ||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||
SP4: | - | - | |||||||||||||||||||||||||
SP5: | - |
Expression for RCHY1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RCHY1 Gene
NURSA nuclear receptor signaling pathways regulating expression of RCHY1 Gene:
RCHY1SOURCE GeneReport for Unigene cluster for RCHY1 Gene:
Hs.48297Evidence on tissue expression from TISSUES for RCHY1 Gene
- Nervous system(4.8)
- Blood(4.3)
- Kidney(2.5)
- Heart(2.2)
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RCHY1 Gene
Orthologs for RCHY1 Gene
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | RCHY1 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | RCHY1 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | RCHY1 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Rchy1 33 16 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | RCHY1 34 |
|
OneToOne | |
rat (Rattus norvegicus) |
Mammalia | Rchy1 33 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | RCHY1 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | RCHY1 33 34 |
|
||
tropical clawed frog (Silurana tropicalis) |
Amphibia | rchy1 33 |
|
||
Str.10607 33 |
|
||||
zebrafish (Danio rerio) |
Actinopterygii | rchy1 33 34 |
|
||
fruit fly (Drosophila melanogaster) |
Insecta | CG16947 33 34 |
|
||
thale cress (Arabidopsis thaliana) |
eudicotyledons | AT3G62970 33 |
|
||
rice (Oryza sativa) |
Liliopsida | Os12g0538500 33 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.11347 34 |
|
OneToOne |
- Species where no ortholog for RCHY1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for RCHY1 Gene
(1) SIMAP similar genes for RCHY1 Gene using alignment to 7 proteins:
No data available for Paralogs for RCHY1 Gene
Variants for RCHY1 Gene
SNP ID | Clin | Chr 04 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000067470 | -- | 75,503,687(-) | A/AA | intron_variant | |
rs1000096697 | -- | 75,503,989(-) | G/T | intron_variant | |
rs1000234603 | -- | 75,478,554(-) | G/A | downstream_transcript_variant | |
rs1000253883 | -- | 75,510,787(-) | A/C | intron_variant | |
rs1000365525 | -- | 75,511,059(-) | A/G | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1111276 | CNV | tandem duplication | 24896259 |
nsv1131809 | CNV | deletion | 24896259 |
nsv1140180 | CNV | insertion | 24896259 |
nsv1143097 | CNV | tandem duplication | 24896259 |
nsv594687 | CNV | loss | 21841781 |
nsv7363 | OTHER | inversion | 18451855 |
Additional Variant Information for RCHY1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RCHY1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RCHY1 Gene
Disorders for RCHY1 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
variola minor |
|
|
Additional Disease Information for RCHY1
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for RCHY1 Gene
Publications for RCHY1 Gene
- Molecular basis of Pirh2-mediated p53 ubiquitylation. (PMID: 19043414) Sheng Y … Arrowsmith CH (Nature structural & molecular biology 2008) 3 4 22 58
- PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53. (PMID: 17950244) Zheng G … Yang YC (Biochemical and biophysical research communications 2007) 3 4 22 58
- Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome. (PMID: 14701804) Logan IR … Robson CN (The Journal of biological chemistry 2004) 3 4 22 58
- Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. (PMID: 12654245) Leng RP … Benchimol S (Cell 2003) 2 3 22 58
- Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. (PMID: 22491018) Wang J … Platt A (The pharmacogenomics journal 2013) 3 44 58
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- Invitrogen Antibodies for RCHY1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for RCHY1
- VectorBuilder custom plasmid, inducible vectors for RCHY1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RCHY1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for RCHY1
- antibodies-online: Search results for 53 available RCHY1 Antibodies ranked by validation data
- Compare Top RCHY1 Antibodies
- antibodies-online: Search results for available RCHY1 related products ranked by validation data
- antibodies-online: Search results for 5 available RCHY1 Proteins ranked by validation data
- Compare Top RCHY1 Proteins
- Quality Products:
- GeneTex RCHY1 antibody for RCHY1
- Search GeneTex for Proteins for RCHY1
- ViGene Biosciences adenoviral particle packaged cDNA for RCHY1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for RCHY1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for RCHY1 gene
- Search ViGene Biosciences for RCHY1
- Santa Cruz Biotechnology (SCBT) Antibodies for RCHY1
- Search Santa Cruz Biotechnology (SCBT) for RCHY1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RCHY1
- Horizon Cell Lines for RCHY1
- genomics-online: cdna clones - Search results for available RCHY1 gene related products
- orf clones - Search results for available RCHY1 gene related products
- genomics-online: gRNA clones - Search results for available RCHY1 gene related products
- genomics-online: primer clones - Search results for available RCHY1 gene related products
- genomics-online: shRNA clones - Search results for available RCHY1 gene related products
Sources for RCHY1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew