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Aliases for RPL36 Gene

Aliases for RPL36 Gene

  • Ribosomal Protein L36 2 3
  • 60S Ribosomal Protein L36 3
  • RPL36A 6
  • RPL44 6
  • L36 3

External Ids for RPL36 Gene

Previous GeneCards Identifiers for RPL36 Gene

  • GC19P005782
  • GC19P005621
  • GC19P005641
  • GC19P005451

Summaries for RPL36 Gene

Entrez Gene Summary for RPL36 Gene

  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L36E family of ribosomal proteins. It is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

GeneCards Summary for RPL36 Gene

RPL36 (Ribosomal Protein L36) is a Protein Coding gene. Among its related pathways are Disease and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for RPL36 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL36 Gene

Genomics for RPL36 Gene

Regulatory Elements for RPL36 Gene

Genomic Location for RPL36 Gene

Start:
5,674,947 bp from pter
End:
5,691,876 bp from pter
Size:
16,930 bases
Orientation:
Plus strand

Genomic View for RPL36 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RPL36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL36 Gene

Proteins for RPL36 Gene

  • Protein details for RPL36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y3U8-RL36_HUMAN
    Recommended name:
    60S ribosomal protein L36
    Protein Accession:
    Q9Y3U8
    Secondary Accessions:
    • B2R4Y1
    • D6W634
    • Q6FIG1
    • Q9UQF6

    Protein attributes for RPL36 Gene

    Size:
    105 amino acids
    Molecular mass:
    12254 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RPL36 Gene

neXtProt entry for RPL36 Gene

Proteomics data for RPL36 Gene at MOPED

Post-translational modifications for RPL36 Gene

  • Ubiquitination at Lys62
  • Modification sites at PhosphoSitePlus

Other Protein References for RPL36 Gene

No data available for DME Specific Peptides for RPL36 Gene

Domains for RPL36 Gene

Gene Families for RPL36 Gene

HGNC:
  • RPL :L ribosomal proteins

Protein Domains for RPL36 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for RPL36 Gene

Graphical View of Domain Structure for InterPro Entry

Q9Y3U8

UniProtKB/Swiss-Prot:

RL36_HUMAN :
  • Q9Y3U8
Family:
  • Belongs to the ribosomal protein L36e family.
genes like me logo Genes that share domains with RPL36: view

Function for RPL36 Gene

Gene Ontology (GO) - Molecular Function for RPL36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome NAS 12962325
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RPL36: view
genes like me logo Genes that share phenotypes with RPL36: view

miRNA for RPL36 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RPL36 Gene

Localization for RPL36 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RPL36 Gene COMPARTMENTS Subcellular localization image for RPL36 gene
Compartment Confidence
cytosol 5
nucleus 4
chloroplast 2
mitochondrion 2

Gene Ontology (GO) - Cellular Components for RPL36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IDA --
GO:0005829 cytosol TAS --
GO:0005840 ribosome --
genes like me logo Genes that share ontologies with RPL36: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RPL36 Gene

Pathways for RPL36 Gene

genes like me logo Genes that share pathways with RPL36: view

Pathways by source for RPL36 Gene

1 KEGG pathway for RPL36 Gene
1 GeneGo (Thomson Reuters) pathway for RPL36 Gene

Gene Ontology (GO) - Biological Process for RPL36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS --
GO:0006412 translation TAS --
GO:0006413 translational initiation TAS --
GO:0006414 translational elongation TAS --
GO:0006415 translational termination TAS --
genes like me logo Genes that share ontologies with RPL36: view

Transcripts for RPL36 Gene

Unigene Clusters for RPL36 Gene

Ribosomal protein L36:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RPL36 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
SP1:
SP2:

Relevant External Links for RPL36 Gene

GeneLoc Exon Structure for
RPL36
ECgene alternative splicing isoforms for
RPL36

Expression for RPL36 Gene

mRNA expression in normal human tissues for RPL36 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RPL36 Gene

SOURCE GeneReport for Unigene cluster for RPL36 Gene Hs.408018

genes like me logo Genes that share expressions with RPL36: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPL36 Gene

Orthologs for RPL36 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPL36 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RPL36 35
  • 99.37 (n)
  • 100 (a)
RPL36 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 92 (a)
OneToMany
-- 36
  • 88 (a)
OneToMany
RPL36 35
  • 90.16 (n)
  • 99.05 (a)
RPL36 36
  • 99 (a)
OneToMany
dog
(Canis familiaris)
Mammalia RPL36 35
  • 91.84 (n)
  • 100 (a)
RPL36 36
  • 57 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm4604 35
  • 86.98 (n)
  • 99.05 (a)
Rpl36 16
Rpl36-ps3 36
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 91 (a)
OneToMany
-- 36
  • 98 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia RPL36 36
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rpl36 35
  • 86.67 (n)
  • 99.05 (a)
chicken
(Gallus gallus)
Aves RPL36 36
  • 100 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.29254 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.8714 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8943 35
zebrafish
(Danio rerio)
Actinopterygii Dr.1335 35
rpl36 36
  • 92 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta RpL36 36
  • 60 (a)
OneToOne
RpL36 37
  • 62 (a)
worm
(Caenorhabditis elegans)
Secernentea rpl-36 36
  • 57 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL36A 36
  • 45 (a)
OneToMany
RPL36B 36
  • 46 (a)
OneToMany
RPL36B 38
soybean
(Glycine max)
eudicotyledons Gma.1156 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4420 36
  • 73 (a)
OneToOne
Species with no ortholog for RPL36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPL36 Gene

ENSEMBL:
Gene Tree for RPL36 (if available)
TreeFam:
Gene Tree for RPL36 (if available)

Paralogs for RPL36 Gene

genes like me logo Genes that share paralogs with RPL36: view

No data available for Paralogs for RPL36 Gene

Variants for RPL36 Gene

Sequence variations from dbSNP and Humsavar for RPL36 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1049958 -- 5,690,483(+) CGCCC(C/T)TTCTC utr-variant-5-prime, intron-variant
rs2297766 -- 5,690,761(-) GAGCA(A/C)CAGGC intron-variant
rs3810219 -- 5,690,405(-) CACAA(C/T)CAACC utr-variant-5-prime, intron-variant
rs3810220 -- 5,690,293(-) AAGGG(C/T)TGGCG upstream-variant-2KB, utr-variant-5-prime
rs10419745 -- 5,690,303(+) TCCGC(C/G)ACGGC upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for RPL36 Gene

Variant ID Type Subtype PubMed ID
dgv3693n71 CNV Loss 21882294
nsv910894 CNV Loss 21882294
dgv3694n71 CNV Loss 21882294
dgv3695n71 CNV Loss 21882294

Relevant External Links for RPL36 Gene

HapMap Linkage Disequilibrium report
RPL36
Human Gene Mutation Database (HGMD)
RPL36

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPL36 Gene

Disorders for RPL36 Gene

(1) University of Copenhagen DISEASES for RPL36 Gene

genes like me logo Genes that share disorders with RPL36: view

No data available for UniProtKB/Swiss-Prot for RPL36 Gene

Publications for RPL36 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 3 4
  3. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PMID: 11875025) Yoshihama M. … Kenmochi N. (Genome Res. 2002) 3 4
  5. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. (PMID: 12962325) Odintsova T.I. … Karpova G.G. (J. Protein Chem. 2003) 3 4

Products for RPL36 Gene

Sources for RPL36 Gene

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