Aliases for FSCN2 Gene
External Ids for FSCN2 Gene
Previous GeneCards Identifiers for FSCN2 Gene
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for FSCN2 Gene
FSCN2 (Fascin Actin-Bundling Protein 2, Retinal) is a Protein Coding gene. Diseases associated with FSCN2 include Retinitis Pigmentosa 30 and Fscn2-Related Retinitis Pigmentosa. GO annotations related to this gene include actin binding and protein binding, bridging. An important paralog of this gene is FSCN1.
UniProtKB/Swiss-Prot for FSCN2 Gene
Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.