Aliases for ALPI Gene
External Ids for ALPI Gene
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014]
GeneCards Summary for ALPI Gene
ALPI (Alkaline Phosphatase, Intestinal) is a Protein Coding gene. Diseases associated with ALPI include soft palate cancer and hypophosphatasia. Among its related pathways are Metabolism and Nicotinate and nicotinamide metabolism. GO annotations related to this gene include alkaline phosphatase activity. An important paralog of this gene is ALPL.