Aliases for LDOC1 Gene
External Ids for LDOC1 Gene
Previous HGNC Symbols for LDOC1 Gene
Previous GeneCards Identifiers for LDOC1 Gene
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]
GeneCards Summary for LDOC1 Gene
LDOC1 (Leucine Zipper, Down-Regulated In Cancer 1) is a Protein Coding gene. An important paralog of this gene is FAM127B.
UniProtKB/Swiss-Prot for LDOC1 Gene
May have an important role in the development and/or progression of some cancers.