Aliases for TSSK2 Gene
External Ids for TSSK2 Gene
Previous HGNC Symbols for TSSK2 Gene
Previous GeneCards Identifiers for TSSK2 Gene
TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008]
GeneCards Summary for TSSK2 Gene
TSSK2 (Testis Specific Serine Kinase 2) is a Protein Coding gene. Diseases associated with TSSK2 include Velocardiofacial Syndrome. Among its related pathways are Sweet Taste Signaling and Transcription_CREM signaling in testis. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TSSK6.
UniProtKB/Swiss-Prot for TSSK2 Gene
Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at Ser-288 and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.