Aliases for GRIP1 Gene
External Ids for GRIP1 Gene
Previous GeneCards Identifiers for GRIP1 Gene
This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 2010]
GeneCards Summary for GRIP1 Gene
GRIP1 (Glutamate Receptor Interacting Protein 1) is a Protein Coding gene. Diseases associated with GRIP1 include Fraser Syndrome 3 and Cryptophthalmos. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Trafficking of AMPA receptors. GO annotations related to this gene include transcription coactivator activity and beta-catenin binding. An important paralog of this gene is GRIP2.
UniProtKB/Swiss-Prot for GRIP1 Gene
May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.