Aliases for TDRD7 Gene
External Ids for TDRD7 Gene
Previous GeneCards Identifiers for TDRD7 Gene
The protein encoded by this gene belongs to the Tudor family of proteins. This protein contains conserved Tudor domains and LOTUS domains. It is a component of RNA granules, which function in RNA processing. Mutations in this gene have been associated with cataract formation in mouse and human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
GeneCards Summary for TDRD7 Gene
TDRD7 (Tudor Domain Containing 7) is a Protein Coding gene. Diseases associated with TDRD7 include cataract 36 and cataract. Among its related pathways are Aurora A signaling. GO annotations related to this gene include protein N-terminus binding and mRNA binding. An important paralog of this gene is TDRKH.
UniProtKB/Swiss-Prot for TDRD7 Gene
Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.