Aliases for NCAPH Gene
External Ids for NCAPH Gene
Previous HGNC Symbols for NCAPH Gene
Previous GeneCards Identifiers for NCAPH Gene
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]
GeneCards Summary for NCAPH Gene
NCAPH (Non-SMC Condensin I Complex Subunit H) is a Protein Coding gene. Diseases associated with NCAPH include Uterine Corpus Endometrial Carcinoma and Uterine Corpus Cancer. Among its related pathways are Mitotic Prometaphase and Aurora B signaling.
UniProtKB/Swiss-Prot for NCAPH Gene
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.