Aliases for EXOC7 Gene
External Ids for EXOC7 Gene
Previous GeneCards Identifiers for EXOC7 Gene
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]
GeneCards Summary for EXOC7 Gene
EXOC7 (Exocyst Complex Component 7) is a Protein Coding gene. Diseases associated with EXOC7 include eastern equine encephalitis. Among its related pathways are Actin Nucleation by ARP-WASP Complex and CDC42 signaling events.
UniProtKB/Swiss-Prot for EXOC7 Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity).