Aliases for SIK2 Gene
External Ids for SIK2 Gene
Previous HGNC Symbols for SIK2 Gene
Previous GeneCards Identifiers for SIK2 Gene
GeneCards Summary for SIK2 Gene
SIK2 (Salt-Inducible Kinase 2) is a Protein Coding gene. Among its related pathways are Glucose / Energy Metabolism and LKB1 signaling events. GO annotations related to this gene include protein serine/threonine kinase activity and magnesium ion binding. An important paralog of this gene is MARK4.
UniProtKB/Swiss-Prot for SIK2 Gene
Phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.